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Endovascular Stroke Therapy with a Novel 6-French Aspiration Catheter

  • Clinical Investigation
  • Stroke/Neurointerventions
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Background and Purpose

Direct thrombus aspiration is increasingly used as a first-line therapy in acute ischemic stroke with large vessel occlusion. We assessed the performance and safety of a novel aspiration catheter available: the 6-French AXS Catalyst catheter.

Materials and Methods

We conducted a cohort study from a prospective clinical registry of consecutive stroke patients treated by mechanical thrombectomy between March 2016 and July 2016. Baseline clinical and imaging characteristics, recanalization rates, complications, and clinical outcomes were analyzed.

Results

Among the 60 patients included, 30 were treated using aspiration alone, 14 were treated using aspiration and then stent retriever as a rescue therapy, and 16 were treated using aspiration combined with a stent retriever straightaway. Successful recanalization (mTICI2b/3) was achieved in 85% patients and functional independence in 48.3%. We observed one intracranial perforation and one vertebral artery dissection. Symptomatic intracranial hemorrhage occurred in 5% and mortality in 21.7%.

Conclusion

Endovascular stroke therapy using the AXS Catalyst catheter seems safe and effective, with similar performance than other reperfusion catheters.

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Abbreviations

AIS:

Acute ischemic stroke

ADAPT:

A Direct Aspiration First Pass Technique

HI:

Hemorrhagic infarction

ICA:

Internal carotid artery

IVT:

Intravenous thrombolysis

LVO:

Large vessel occlusion

MCA:

Middle cerebral artery

MT:

Mechanical thrombectomy

mTICI:

Modified Thrombolysis In Cerebral Infarction

PH:

Parenchymal hemorrhage

sICH:

Symptomatic intracerebral hemorrhage

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Funding

This work was supported by Stryker Neurovascular. The funding source was not involved in study design, monitoring, data collection, statistical analyses, interpretation of results, or manuscript writing.

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Authors and Affiliations

  1. Department of Interventional Neuroradiology, University of Lille, Hopital Roger Salengro – CHU Lille, 59800, Lille, France

    M. Bretzner, L. Estrade, F. Bala, A. Kazemi, J. P. Pruvo & N. Bricout

  2. Department of Neurology, University of Lille, CHU Lille, Lille, France

    M. Ferrigno & H. Henon

  3. Department of Interventional Neuroradiology, University of Tours, CHU Tours, Tours, France

    F. Boustia

  4. INSERM U1171 - Degenerative and Vascular Cognitive Disorders, Lille, France

    M. Bretzner, M. Ferrigno, J. P. Pruvo & H. Henon

Authors
  1. M. Bretzner
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  2. L. Estrade
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  3. M. Ferrigno
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  4. F. Bala
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  5. F. Boustia
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  6. A. Kazemi
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  7. J. P. Pruvo
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  8. H. Henon
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  9. N. Bricout
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Corresponding author

Correspondence to N. Bricout.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

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Consent for publication was obtained for every individual person’s data included in the study.

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Bretzner, M., Estrade, L., Ferrigno, M. et al. Endovascular Stroke Therapy with a Novel 6-French Aspiration Catheter. Cardiovasc Intervent Radiol 42, 110–115 (2019). https://doi.org/10.1007/s00270-018-2093-y

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  • DOI: https://doi.org/10.1007/s00270-018-2093-y

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