Skip to main content
SpringerLink
Log in

CT-Guided RFA for Management of Surgical Relapses of Giant Cell Tumour of Bone

  • Short Communication
  • Musculoskeletal Interventions
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Objectives

This retrospective study describes a pilot experience in CT-guided RadioFrequency Ablation (RFA) treatment of 5 Giant Cell Tumour of the bone (GCT) recurrences after surgery.

Methods

After biopsy to confirm the diagnosis of GCT recurrences, all patients were treated with RFA in a single session. A close follow-up was scheduled with contrast-enhanced MRI starting 1 months after treatment.

Results

Five lesions were treated in 5 patients. The length of the observation period was between 4 and 100 months. One lesion relapsed 4 months after the RFA treatment, and the patient underwent a second surgical treatment which included the en-block resection and prosthetic implant. No complications were recorded.

Conclusions

The management of GCT relapses with RFA could be an interesting and innovative field. However, the results of this limited series need to be confirmed by further investigations of larger patient cohorts.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

References

  1. Chakarun CJ, Forrester DM, Gottsegen CJ, Patel DB, White EA, Matcuk GR Jr. Giant cell tumor of bone: review, mimics, and new developments in treatment. Radiographics. 2013;33:197–211.

    Article  PubMed  Google Scholar 

  2. Rossi B, Ferraresi V, Appetecchia ML, Novello M, Zoccali C. Giant cell tumor of bone in a patient with diagnosis of primary hyperparathyroidism: a challenge in differential diagnosis with brown tumor. Skelet Radiol. 2014;43:693–7.

    Article  Google Scholar 

  3. Mavrogenis AF, Igoumenou VG, Megaloikonomos PD, Panagopoulos GN, Papagelopoulos PJ, Soucacos PN. Giant cell tumor of bone revisited. Sicot-j. 2017;3:54.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Lin X, Liu J, Xu M. The prognosis of giant cell tumor of bone and the vital risk factors that affect its postoperative recurrence: a meta-analysis. Transl Cancer Res. 2021;10:1712–22.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Arrigoni F, Barile A, Zugaro L, Fascetti E, Zappia M, Brunese L, et al. CT-guided radiofrequency ablation of spinal osteoblastoma: treatment and long-term follow-up. Int J Hyperth. 2018;34:321–7.

    Article  Google Scholar 

  6. Cazzato RL, Palussière J, Auloge P, Rousseau C, Koch G, Dalili D, et al. Complications following percutaneous image-guided radiofrequency ablation of bone tumors: a 10-year dual-center experience. Radiology. 2020;296:227–35.

    Article  PubMed  Google Scholar 

  7. Jiao Y, Yang H, Xu L, Liu J, Hu Y. Surgical treatment of distal radius giant cell tumors. Hand Surgery Rehabil. 2021;40:150–5.

    Article  Google Scholar 

  8. Rigollino AV, Fernando TS, Tanaka MH, Souza MM. Tumor de células gigantes localmente avançado ao nível do joelho: tratamento e revisão da literatura. Rev Bras Ortop. 2017;52:473–8.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Arrigoni F, Bruno F, Gianneramo C, Palumbo P, Zugaro L, Zoccali C, et al. Evolution of the imaging features of osteoid osteoma treated with RFA or MRgFUS during a long-term follow-up: a pictorial review with clinical correlations. Radiol Med. 2020;81:295–9.

    Google Scholar 

Download references

Funding

This study was not supported by any funding.

Author information

Authors and Affiliations

  1. Department of Emergency and Interventional Radiology, San Salvatore Hospital, Via Vetoio, 67010, Coppito, L’Aquila, Italy

    Francesco Arrigoni & Luigi Zugaro

  2. Oncological Orthopedics University “Sapienza” of Rome, Rome, Italy

    Carmine Zoccali

  3. Oncological Orthopedics Unit, IRCCS Regina Elena National Cancer Institute, 00144, Rome, Italy

    Carmine Zoccali

  4. Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

    Laura Evangelista, Luca Giuliani, Julia Daffinà & Carlo Masciocchi

Authors
  1. Francesco Arrigoni
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Carmine Zoccali
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Laura Evangelista
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Luca Giuliani
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Julia Daffinà
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Luigi Zugaro
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Carlo Masciocchi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Francesco Arrigoni.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Consent for Publication

Consent for publication was obtained for every individual person's data included in the study.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed Consent

This study has obtained IRB approval from (Internal Review board of the University of L’Aquila. N. 28/2022), and the need for informed consent was waived.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Arrigoni, F., Zoccali, C., Evangelista, L. et al. CT-Guided RFA for Management of Surgical Relapses of Giant Cell Tumour of Bone. Cardiovasc Intervent Radiol 46, 508–511 (2023). https://doi.org/10.1007/s00270-023-03382-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00270-023-03382-5

Keywords

Search

Navigation