Abstract
Purpose of Review
Our objective is to summarize the most recent, high-quality data regarding perioperative recommendations for hysterectomy and salpingo-oophorectomy in transgender and gender nonconforming individuals.
Recent Findings
Many transgender men desire hysterectomy and salpingo-oophorectomy for gender affirmation, cancer-risk reduction, pelvic pain, or abnormal uterine bleeding. Gender-confirming hysterectomy is safe, effective, and highly beneficial for well-counseled patients. Preoperative considerations include optimizing the office environment, preoperative testing specific to patients with long-term testosterone use, counseling specific to transgender men, consideration of World Professional Association for Transgender Health criteria, and coordination of a multi-disciplinary team. Minimally invasive approaches, including vaginal, laparoscopic, and robotic-assisted hysterectomy, are the standard of care for cisgender women and transgender men given lower complication rates, better post-operative outcomes, and greater cosmetic satisfaction. Concurrent appendectomy, mastectomy, vaginectomy, and urethral reconstruction may be performed at the time of hysterectomy; phalloplasty and metoidioplasty are generally performed as subsequent procedures. Same-day discharge following hysterectomy is safe and has been shown to improve post-operative outcomes. We recommend follow-up with the patient’s mental health professional and endocrinologist in addition to routine surgical follow-up. Long-term satisfaction after genital surgery appears to be high and regret is low.
Summary
More robust and up to date research is needed to improve guidelines and perioperative care for transgender individuals. Available data suggests that hysterectomy and salpingo-oophorectomy for transgender men is safe, is not associated with any additional risks compared to cisgender women, and is associated with an improved quality of life.
Similar content being viewed by others
References
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
Hage JJ, Bloem JJ. Review of the literature on construction of a neourethra in female-to-male transsexuals. Ann Plast Surg. 1993;30(3):278–86.
• Unger CA. Care of the transgender patient: the role of the gynecologist. Am J Obstet Gynecol. 2014;210(1):16–26. This article provides a succinct overview of hormonal and surgical treatment for gynecology providers
Aydin D, et al. Transgender surgery in Denmark from 1994 to 2015: 20-year follow-up study. J Sex Med. 2016;13(4):720–5.
De Cuypere G, et al. Sexual and physical health after sex reassignment surgery. Arch Sex Behav. 2005;34(6):679–90.
Gooren LJ. Management of female-to-male transgender persons: medical and surgical management, life expectancy. Curr Opin Endocrinol Diabetes Obes. 2014;21(3):233–8.
Wierckx K, et al. Quality of life and sexual health after sex reassignment surgery in transsexual men. J Sex Med. 2011;8(12):3379–88.
Pfäfflin F. Regrets after sex reassignment surgery. Journal of Psychology & Human Sexuality. 1992;5(4):69–85.
Klein C, Gorzalka BB. Sexual functioning in transsexuals following hormone therapy and genital surgery: a review. J Sex Med. 2009;6(11):2922–39. quiz 2940-1
Gijs L, Brewaeys A. Surgical treatment of gender dysphoria in adults and adolescents: recent developments, effectiveness, and challenges. Annual Review of Sex Research. 2007;18(1):178–224.
Peitzmeier SM, et al. Pap test use is lower among female-to-male patients than non-transgender women. Am J Prev Med. 2014;47(6):808–12.
•• Committee Opinion no. 512: health care for transgender individuals. Obstet Gynecol. 2011;118(6): p. 1454–8.This article provides practical and actionable guidelines for all obstetricians and gynecologists from the American College of Obstetricians and Gynecologists, an internationally-recognized source of information and governing body.
•• Health, W.P.A.f.T. The Harry Benjamin International Gender Dysphoria Association’s standards of care for gender identity disorders. 2011 [cited 2016 December 20]; 7th:[Available from: http://www.wpath.org/site_page.cfm?pk_association_webpage_menu=1351. A document that provides a summary of pertinent information and guidelines for hormone use and surgery; considered by most experts in the field of transgender care to be standard criteria for treatment of transgender, transsexual, and gender nonconforming individuals.
Unger CA. Care of the transgender patient: a survey of gynecologists’ current knowledge and practice. J Women's Health (Larchmt). 2015;24(2):114–8.
Weyers S, et al. Gynaecological aspects of the treatment and follow-up of transsexual men and women. Facts Views Vis Obgyn. 2010;2(1):35–54.
Peitzmeier SM, et al. Female-to-male patients have high prevalence of unsatisfactory Paps compared to non-transgender females: implications for cervical cancer screening. J Gen Intern Med. 2014;29(5):778–84.
Massad LS, et al. 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. Obstet Gynecol. 2013;121(4):829–46.
• Feely MA, et al. Preoperative testing before noncardiac surgery: guidelines and recommendations. Am Fam Physician. 2013;87(6):414–8. A helpful review of indicated preoperative testing prior to gynecologic surgery
Wierckx K, et al. Long-term evaluation of cross-sex hormone treatment in transsexual persons. J Sex Med. 2012;9(10):2641–51.
O'Hanlan KA, Dibble SL, Young-Spint M. Total laparoscopic hysterectomy for female-to-male transsexuals. Obstet Gynecol. 2007;110(5):1096–101.
Ott J, et al. Combined hysterectomy/salpingo-oophorectomy and mastectomy is a safe and valuable procedure for female-to-male transsexuals. J Sex Med. 2010;7(6):2130–8.
Universal Protocol. 2012 [cited 2017 March 23]; Available from: https://www.jointcommission.org/standards_information/up.aspx.
AAGL position statement: route of hysterectomy to treat benign uterine disease. J Minim Invasive Gynecol. 2011;18(1): p. 1–3.
ACOG Committee Opinion No. 444: choosing the route of hysterectomy for benign disease. Obstet Gynecol. 2009;114(5): p. 1156–8.
Bogliolo S, et al. Robotic single site hysterectomy with bilateral salpingo-oophorectomy in female to male transsexualism. J Sex Med. 2014;11(1):313.
Bartos P, Struppl D, Popelka P. Role of total laparoscopic hysterectomy in genital reconstruction in transsexuals. Ceska Gynekol. 2001;66(3):193–5.
Filova P, et al. Comparison of hysterectomy techniques in a group of patient operated for the diagnosis female to male transsexualism. Ceska Gynekol. 2014;79(1):68–74.
Groenman, F., et al., Robot-assisted laparoscopic colpectomy in female-to-male transgender patients; technique and outcomes of a prospective cohort study. Surg Endosc. 2016.
Obedin-Maliver J, et al. Feasibility of vaginal hysterectomy for female-to-male transgender men. Obstet Gynecol. 2017;129(3):457–63.
Kaiser C, et al. Vaginal hysterectomy and bilateral adnexectomy for female to male transsexuals in an interdisciplinary concept. Handchir Mikrochir Plast Chir. 2011;43(4):240–5.
Sandberg EM, et al. Total laparoscopic hysterectomy versus vaginal hysterectomy: a systematic review and meta-analysis. J Minim Invasive Gynecol. 2017;24(2):206–17. e22
Hur HC, et al. Incidence and patient characteristics of vaginal cuff dehiscence after different modes of hysterectomies. J Minim Invasive Gynecol. 2007;14(3):311–7.
Uccella S, et al. Vaginal cuff dehiscence in a series of 12,398 hysterectomies: effect of different types of colpotomy and vaginal closure. Obstet Gynecol. 2012;120(3):516–23.
Tulandi T, Einarsson JI. The use of barbed suture for laparoscopic hysterectomy and myomectomy: a systematic review and meta-analysis. J Minim Invasive Gynecol. 2014;21(2):210–6.
Einarsson JI, et al. Barbed versus standard suture: a randomized trial for laparoscopic vaginal cuff closure. J Minim Invasive Gynecol. 2013;20(4):492–8.
Siedhoff MT, Yunker AC, Steege JF. Decreased incidence of vaginal cuff dehiscence after laparoscopic closure with bidirectional barbed suture. J Minim Invasive Gynecol. 2011;18(2):218–23.
Rettenmaier MA, et al. Dramatically reduced incidence of vaginal cuff dehiscence in gynecologic patients undergoing endoscopic closure with barbed sutures: a retrospective cohort study. Int J Surg. 2015;19:27–30.
Tsafrir Z, et al. Long-term outcomes for different vaginal cuff closure techniques in robotic-assisted laparoscopic hysterectomy: a randomized controlled trial. Eur J Obstet Gynecol Reprod Biol. 2016;210:7–12.
Bogliolo S, et al. Barbed suture in minimally invasive hysterectomy: a systematic review and meta-analysis. Arch Gynecol Obstet. 2015;292(3):489–97.
Unger CA. Laparoscopic gender confirmation surgery. J Minim Invasive Gynecol. 2016;23(3):291.
• Gomes da Costa A, et al. Laparoscopic vaginal-assisted hysterectomy with complete vaginectomy for female-to-male genital reassignment surgery. J Minim Invasive Gynecol. 2016;23(3):404–9. A detailed outline of genital surgery from hysterectomy to phalloplasty, performed in a two-stage fashion. This article provides a guide for concurrent hysterectomy, bilateral salpingoophorectomy, and complete vaginectomy with urethral reconstruction with exceptional patient outcomes, short operative time, and few complications
Rohrmann D, Jakse G. Urethroplasty in female-to-male transsexuals. Eur Urol. 2003;44(5):611–4.
Monstrey SJ, Ceulemans P, Hoebeke P. Sex reassignment surgery in the female-to-male transsexual. Semin Plast Surg. 2011;25(3):229–44.
Selvaggi G, et al. Scrotal reconstruction in female-to-male transsexuals: a novel scrotoplasty. Plast Reconstr Surg. 2009;123(6):1710–8.
Perron-Burdick M, Yamamoto M, Zaritsky E. Same-day discharge after laparoscopic hysterectomy. Obstet Gynecol. 2011;117(5):1136–41.
Jennings AJ, et al. Predictors of 30-day readmission and impact of same-day discharge in laparoscopic hysterectomy. Am J Obstet Gynecol. 2015;213(3):344. e1-7
Donnez O, et al. Low pain score after total laparoscopic hysterectomy and same-day discharge within less than 5 hours: results of a prospective observational study. J Minim Invasive Gynecol. 2015;22(7):1293–9.
Schiavone MB, et al. Feasibility and economic impact of same-day discharge for women who undergo laparoscopic hysterectomy. Am J Obstet Gynecol. 2012;207(5):382. e1-9
Kalogera E, Dowdy SC. Enhanced recovery pathway in gynecologic surgery: improving outcomes through evidence-based medicine. Obstet Gynecol Clin N Am. 2016;43(3):551–73.
Phillips J, et al. Breast imaging in the transgender patient. AJR Am J Roentgenol. 2014;202(5):1149–56.
Landen M, et al. Factors predictive of regret in sex reassignment. Acta Psychiatr Scand. 1998;97(4):284–9.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of Interest
Michelle Louie and Janelle K. Moulder declare payment from Teleflex Medical for consultancy work.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Additional information
This article is part of the Topical Collection on Care for the Transgender Patient
Rights and permissions
About this article
Cite this article
Louie, M., Moulder, J.K. Hysterectomy for the Transgender Man. Curr Obstet Gynecol Rep 6, 126–132 (2017). https://doi.org/10.1007/s13669-017-0211-5
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13669-017-0211-5