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Brain Oscillatory Activity and Neurological Deficit in Hyper-acute Ischemic Stroke: Correlation of EEG Changes with NIHSS

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XV Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019 (MEDICON 2019)

Part of the book series: IFMBE Proceedings ((IFMBE,volume 76))

Abstract

The accurate identification and prediction of cerebral infarct evolution and clinical outcome are of paramount importance in acute ischemic stroke management. Neuroimaging in acute stroke is mandatory to establish the feasibility of reperfusion therapy, but it is not practical to assess the continuous evolution of brain ischemia. EEG could be an applicable instrument to perform functional monitoring in the hyper-acute phase. EEG activity during ischemic stroke has been widely studied in sub-acute and post-acute phase of ischemic stroke. However, only few studies have focused on the early phase of brain ischemia. The aim of this study conducted at the stroke unit was to investigate stroke-related EEG changes during the earliest phase of ischemic stroke within 4.5 h from symptom onset and to correlate these data with neurological deficit in terms of NIHSS score. We studied 12 patients with ischemic stroke, who underwent EEG recordings within 4.5 h from symptom onset. The EEG signals acquisition was performed bedside without delaying reperfusion treatment, using @64 channels Wi-Fi Be Plus LTM amplifier and 19 channel 10–20 Ag/AgCl electrodes wireless prewired headset. The main finding of this study is a significant positive correlation between stroke-related EEG changes measured by DAR and DTABR parameters and the neurological deficit measured by NIHSS score, during the earliest phase of ischemic stroke. The results of this study highlight the importance of EEG as complementary tool in the assessment of stroke severity and its potential role in acute decision-making and monitoring.

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Acknowledgements

M. Ajčević is supported by AIRAlzh Onlus - (ANCC-COOP). The authors would like to thank Matteo di Franza for editorial assistance. This study was partially supported by Master in Clinical Engineering, University of Trieste.

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Authors and Affiliations

  1. Neurology Unit, University Hospital of Trieste, Department of Medicine Surgery and Health Sciences, University of Trieste, Trieste, Italy

    Miloš Ajčević, Giovanni Furlanis, Lara Stragapede, Mariana Ridolfi, Paola Caruso, Marcello Naccarato & Paolo Manganotti

  2. Department of Engineering and Architecture, University of Trieste, Trieste, Italy

    Miloš Ajčević & Agostino Accardo

  3. NEUROFARBA Department, Neuroscience Section, University of Florence, Florence, Italy

    Miloš Ajčević

Authors
  1. Miloš Ajčević
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  2. Giovanni Furlanis
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  3. Lara Stragapede
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  4. Mariana Ridolfi
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  5. Paola Caruso
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  6. Marcello Naccarato
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  7. Agostino Accardo
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  8. Paolo Manganotti
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Corresponding author

Correspondence to Miloš Ajčević .

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Editors and Affiliations

  1. University of Coimbra, Coimbra, Portugal

    Jorge Henriques

  2. Universidade do Minho, Braga, Portugal

    Nuno Neves

  3. University of Coimbra, Coimbra, Portugal

    Paulo de Carvalho

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Ajčević, M. et al. (2020). Brain Oscillatory Activity and Neurological Deficit in Hyper-acute Ischemic Stroke: Correlation of EEG Changes with NIHSS. In: Henriques, J., Neves, N., de Carvalho, P. (eds) XV Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019. MEDICON 2019. IFMBE Proceedings, vol 76. Springer, Cham. https://doi.org/10.1007/978-3-030-31635-8_16

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  • DOI: https://doi.org/10.1007/978-3-030-31635-8_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-31634-1

  • Online ISBN: 978-3-030-31635-8

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