Abstract
Gynecomastia means breast enlargement noted in males. It is mostly seen in adolescent males at the time of puberty. It is important to differentiate true gynecomastia from lipomastia especially in obese patients. Occasionally there is an associated underlying systemic or endocrine cause; hence detailed history and physical examination is warranted. If no secondary cause of gynecomastia is found, watchful waiting with regular follow-up is recommended as most cases regress spontaneously. If that is not the case, then medical treatment can be considered, although there are limited randomized clinical trials for medical management of gynecomastia in the pediatric population. Surgical referral can be considered for refractory cases of gynecomastia.
Breast asymmetry can be seen in pubertal adolescent girls and boys due to the fluctuating response of breast tissue to the hormonal environment. Some degree of asymmetry is common and almost always benign. Detailed history and physical examination are necessary to rule out any pathology. If no underlying pathology is suspected, watchful waiting until breast development is complete is reasonable. Surgical referral for cosmetic mammoplasty can be considered for significant breast asymmetry that fails to resolve.
Galactorrhea is defined as breast milk production in males, and in females a year after pregnancy or cessation of breast feeding. Several local and systemic conditions as well as medications can cause galactorrhea and are essential to rule out. Galactorrhea with normal prolactin levels can be observed without treatment. Brain imaging is required if elevated prolactin level without an underlying cause is found. Dopamine agonists are first-line medical therapy for prolactinoma. Patient should be referred to neurosurgery for central nervous system lesions other than prolactinoma.
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References
Narula HS, Carlson HE. Gynaecomastia–pathophysiology, diagnosis and treatment. Nat Rev Endocrinol. 2014;10(11):684–98.
Nicolis GL, Modlinger RS, Gabrilove JL. A study of the histopathology of human gynecomastia. J Clin Endocrinol Metab. 1971;32(2):173–8.
Barros AC, Sampaio MD. Gynecomastia: physiopathology, evaluation and treatment. Sao Paulo Med J. 2012;130(3):187–97.
Reinehr T, Kulle A, Barth A, Ackermann J, Lass N, Holterhus P-M. Sex hormone profile in pubertal boys with gynecomastia and pseudogynecomastia. J Clin Endocrinol Metab. 2020;105(4):dgaa044.
Henley DV, Lipson N, Korach KS, Bloch CA. Prepubertal gynecomastia linked to lavender and tea tree oils. N Engl J Med. 2007;356(5):479–85.
Kanakis GA, Nordkap L, Bang AK, Calogero AE, Bártfai G, Corona G, et al. EAA clinical practice guidelines-gynecomastia evaluation and management. Andrology. 2019;7(6):778–93.
Alonso G, Pasqualini T, Busaniche J, Ruiz E, Chemes H. True hermaphroditism in a phenotypic male without ambiguous genitalia: an unusual presentation at puberty. Horm Res. 2007;68(5):261–4.
Lee EJ, Chang Y-W, Oh JH, Hwang J, Hong SS, Kim H-J. Breast lesions in children and adolescents: diagnosis and management. Korean J Radiol. 2018;19(5):978–91.
Rahmani S, Turton P, Shaaban A, Dall B. Overview of gynecomastia in the modern era and the Leeds Gynaecomastia Investigation algorithm. Breast J. 2011;17(3):246–55.
Spyropoulou G-A, Karamatsoukis S, Foroglou P. Unilateral pseudogynecomastia: an occupational hazard in manual metal-pressing factories? Aesthet Plast Surg. 2011;35(2):270–3.
Nuzzi LC, Cerrato FE, Webb ML, Faulkner HR, Walsh EM, DiVasta AD, et al. Psychological impact of breast asymmetry on adolescents: a prospective cohort study. Plast Reconstr Surg. 2014;134(6):1116–23.
De Silva NK. Breast development and disorders in the adolescent female. Best Pract Res Clin Obstet Gynaecol. 2018 Apr;48:40–50.
Huang W, Molitch ME. Evaluation and management of galactorrhea. Am Fam Physician. 2012;85(11):1073–80.
Watkins F, Giacomantonio M, Salisbury S. Nipple discharge and breast lump related to Montgomery’s tubercles in adolescent females. J Pediatr Surg. 1988;23(8):718–20.
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Shahid, N., Gurtunca, N. (2021). Common Breast Complaints [Gynecomastia, Breast Asymmetry, Galactorrhea]. In: Stanley, T., Misra, M. (eds) Endocrine Conditions in Pediatrics. Springer, Cham. https://doi.org/10.1007/978-3-030-52215-5_13
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DOI: https://doi.org/10.1007/978-3-030-52215-5_13
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