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Hypertension

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Endocrine Conditions in Pediatrics
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Abstract

The prevalence of hypertension (HTN) in youth is lower than that seen in adults; however, clinicians are likely to encounter HTN in children and adolescents with the rising prevalence of obesity. A key component of defining elevated blood pressure (BP) or HTN in youth is the accurate measurement with an appropriate size cuff. The reference ranges for BP depend on age, gender, and height. The American Academy of Pediatrics (AAP) guidelines for the management of hypertension in children and adolescents provide simplified and detailed tables for reference ranges of systolic and diastolic BP and definitions of elevated BP and HTN. A variety of electronic tools and apps have incorporated these guidelines for use at the point of care and are often incorporated into electronic health record systems. The higher prevalence of secondary causes of HTN in youth provides a valuable opportunity for focused therapy and begets a thoughtful assessment by the clinician. Lifestyle management should be advocated for all children with elevated BP or HTN with judicious use of pharmacologic therapy. Maintenance of normal BP in children and adolescents is crucial to the long-term cardiovascular health of our society.

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References

  1. Chen X, Wang Y. Tracking of blood pressure from childhood to adulthood: a systematic review and meta-regression analysis. Circulation. 2008;117(25):3171–80.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Juhola J, Magnussen CG, Berenson GS, Venn A, Burns TL, Sabin MA, et al. Combined effects of child and adult elevated blood pressure on subclinical atherosclerosis: the International Childhood Cardiovascular Cohort Consortium. Circulation. 2013;128(3):217–24.

    Article  PubMed  Google Scholar 

  3. Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, Carroll AE, Daniels SR, et al. Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics. 2017;140(3):e20171904.

    Article  Google Scholar 

  4. Jackson SL, Zhang Z, Wiltz JL, Loustalot F, Ritchey MD, Goodman AB, et al. Hypertension among youths — United States, 2001–2016. Morb Mortal Wkly Rep. 2018;67:758–62.

    Article  Google Scholar 

  5. Gupta-Malhotra M, Banker A, Shete S, Hashmi SS, Tyson JE, Barratt MS, et al. Essential hypertension vs. secondary hypertension among children. Am J Hypertens. 2015;28(1):73–80.

    Article  PubMed  Google Scholar 

  6. MDCalc. AAP Pediatric Hypertension Guidelines: mdcalc.com; 2018 [Web based application to calculate SBP and DBP percentiles for children 1–11 years of age.]. Available from: https://www.mdcalc.com/aap-pediatric-hypertension-guidelines.

  7. Sharma A. AAP 2017: Mobile 2018 [Web based application to calculate SBP and SBP percentile for children aged 2–18 years based on 2017 AAP CPG]. Available from: https://apps.cpeggcep.net/BPz_cpeg_dde/.

  8. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, et al. Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Circulation. 2005;111(5):697–716.

    Article  PubMed  Google Scholar 

  9. American Academy of Pediatrics: Pediatric Elevated Blood Pressure. 2018 [Quality improvement and professional development tools from American Academy of Pediatrics.]. Available from: https://www.aap.org/en-us/professional-resources/quality-improvement/Project-RedDE/Pages/Blood-Pressure.aspx.

  10. Zhang T, Zhang H, Li S, Li Y, Liu Y, Fernandez C, et al. Impact of adiposity on incident hypertension is modified by insulin resistance in adults: longitudinal observation from the Bogalusa heart study. Hypertension. 2016;67(1):56–62.

    Article  CAS  PubMed  Google Scholar 

  11. Sorof JM, Lai D, Turner J, Poffenbarger T, Portman RJ. Overweight, ethnicity, and the prevalence of hypertension in school-aged children. Pediatrics. 2004;113(3 Pt 1):475–82.

    Article  PubMed  Google Scholar 

  12. Sorof J, Daniels S. Obesity hypertension in children: a problem of epidemic proportions. Hypertension. 2002;40(4):441–7.

    Article  CAS  PubMed  Google Scholar 

  13. Skinner AC, Perrin EM, Moss LA, Skelton JA. Cardiometabolic risks and severity of obesity in children and young adults. N Engl J Med. 2015;373(14):1307–17.

    Article  PubMed  Google Scholar 

  14. Lurbe E, Invitti C, Torro I, Maronati A, Aguilar F, Sartorio A, et al. The impact of the degree of obesity on the discrepancies between office and ambulatory blood pressure values in youth. J Hypertens. 2006;24(8):1557–64.

    Article  CAS  PubMed  Google Scholar 

  15. Koebnick C, Black MH, Wu J, Martinez MP, Smith N, Kuizon B, et al. High blood pressure in overweight and obese youth: implications for screening. J Clin Hypertens (Greenwich). 2013;15(11):793–805.

    Article  Google Scholar 

  16. Falkner B, Gidding SS, Ramirez-Garnica G, Wiltrout SA, West D, Rappaport EB. The relationship of body mass index and blood pressure in primary care pediatric patients. J Pediatr. 2006;148(2):195–200.

    Article  PubMed  Google Scholar 

  17. Sharma AK, Metzger DL, Rodd CJ. Prevalence and severity of high blood pressure among children based on the 2017 American Academy of Pediatrics Guidelines. JAMA Pediatr. 2018;172(6):557–65.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Torok K, Palfi A, Szelenyi Z, Molnar D. Circadian variability of blood pressure in obese children. Nutr Metab Cardiovasc Dis. 2008;18(6):429–35.

    Article  CAS  PubMed  Google Scholar 

  19. Westerstahl M, Marcus C. Association between nocturnal blood pressure dipping and insulin metabolism in obese adolescents. Int J Obes. 2010;34(3):472–7.

    Article  CAS  Google Scholar 

  20. Westerstahl M, Hedvall Kallerman P, Hagman E, Ek AE, Rossner SM, Marcus C. Nocturnal blood pressure non-dipping is prevalent in severely obese, prepubertal and early pubertal children. Acta Paediatrica. 2014;103(2):225–30.

    Article  CAS  PubMed  Google Scholar 

  21. Framme J, Dangardt F, Marild S, Osika W, Wahrborg P, Friberg P. 24-h Systolic blood pressure and heart rate recordings in lean and obese adolescents. Clin Physiol Funct Imaging. 2006;26(4):235–9.

    Article  PubMed  Google Scholar 

  22. Ostchega Y, Hughes JP, Nwankwo T, Zhang G. Mean mid-arm circumference and blood pressure cuff sizes for US children, adolescents and adults: National Health and Nutrition Examination Survey, 2011–2016. Blood Press Monit. 2018;23(6):305–11.

    PubMed  PubMed Central  Google Scholar 

  23. Palatini P, Benetti E, Fania C, Malipiero G, Saladini F. Rectangular cuffs may overestimate blood pressure in individuals with large conical arms. J Hypertens. 2012;30(3):530–6.

    Article  CAS  PubMed  Google Scholar 

  24. Bonso E, Saladini F, Zanier A, Benetti E, Dorigatti F, Palatini P. Accuracy of a single rigid conical cuff with standard-size bladder coupled to an automatic oscillometric device over a wide range of arm circumferences. Hypertens Res. 2010;33(11):1186–91.

    Article  PubMed  Google Scholar 

  25. Renda R. Comparison of ambulatory blood pressure monitoring and office blood pressure measurements in obese children and adolescents. Acta Clin Belg. 2018;73(2):126–31.

    Article  PubMed  Google Scholar 

  26. Sarwar N, Gao P, Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010;375(9733):2215–22.

    Article  CAS  PubMed  Google Scholar 

  27. Laing SP, Swerdlow AJ, Slater SD, Burden AC, Morris A, Waugh NR, et al. Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes. Diabetologia. 2003;46(6):760–5.

    Article  CAS  PubMed  Google Scholar 

  28. Schwab KO, Doerfer J, Hecker W, Grulich-Henn J, Wiemann D, Kordonouri O, et al. Spectrum and prevalence of atherogenic risk factors in 27,358 children, adolescents, and young adults with type 1 diabetes: cross-sectional data from the German diabetes documentation and quality management system (DPV). Diabetes Care. 2006;29(2):218–25.

    Article  PubMed  Google Scholar 

  29. Rodriguez BL, Dabelea D, Liese AD, Fujimoto W, Waitzfelder B, Liu L, et al. Prevalence and correlates of elevated blood pressure in youth with diabetes mellitus: the SEARCH for diabetes in youth study. J Pediatr. 2010;157(2):245–51. e1.

    Article  PubMed  Google Scholar 

  30. Margeirsdottir HD, Larsen JR, Brunborg C, Overby NC, Dahl-Jorgensen K, Norwegian Study Group for Childhood Diabetes. High prevalence of cardiovascular risk factors in children and adolescents with type 1 diabetes: a population-based study. Diabetologia. 2008;51(4):554–61.

    Article  CAS  PubMed  Google Scholar 

  31. Lithovius R, Gordin D, Forsblom C, Saraheimo M, Harjutsalo V, Groop PH. Ambulatory blood pressure and arterial stiffness in individuals with type 1 diabetes. Diabetologia. 2018;61(9):1935–45.

    Article  PubMed  Google Scholar 

  32. He FJ, MacGregor GA. Importance of salt in determining blood pressure in children: meta-analysis of controlled trials. Hypertension. 2006;48(5):861–9.

    Article  CAS  PubMed  Google Scholar 

  33. Torrance B, McGuire KA, Lewanczuk R, McGavock J. Overweight, physical activity and high blood pressure in children: a review of the literature. Vasc Health Risk Manag. 2007;3(1):139–49.

    PubMed  PubMed Central  Google Scholar 

  34. Farpour-Lambert NJ, Aggoun Y, Marchand LM, Martin XE, Herrmann FR, Beghetti M. Physical activity reduces systemic blood pressure and improves early markers of atherosclerosis in pre-pubertal obese children. J Am Coll Cardiol. 2009;54(25):2396–406.

    Article  CAS  PubMed  Google Scholar 

  35. Chen HH, Chen YL, Huang CY, Lee SD, Chen SC, Kuo CH. Effects of one-year swimming training on blood pressure and insulin sensitivity in mild hypertensive young patients. Chin J Physiol. 2010;53(3):185–9.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Vidhu V. Thaker .

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Thaker, V.V. (2021). Hypertension. In: Stanley, T., Misra, M. (eds) Endocrine Conditions in Pediatrics. Springer, Cham. https://doi.org/10.1007/978-3-030-52215-5_16

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  • DOI: https://doi.org/10.1007/978-3-030-52215-5_16

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