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Abstract

Serous effusions may be the source of some diagnostic dilemmas due to overlapping cytomorphological findings and a dearth of clinical history. This chapter provides an overview of the spread of benign and malignant conditions that may be encountered in effusion cytology and focuses on some key questions.

The points of distinction between reactive mesothelial and carcinoma are addressed, as well as reactive vs. malignant mesothelial cells. A summary of the helpful panels for specific diagnostic dilemmas is provided, including an update on the various immunohistochemical and molecular markers for mesothelioma.

Finally, specific diagnostic pitfalls are highlighted, along with helpful tips and clues.

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Nga, M.E. (2021). Approach to Effusion Cytology. In: Practical Diagnostic Approaches in Non-Gynaecologic Cytology. Springer, Singapore. https://doi.org/10.1007/978-981-15-2961-0_9

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  • DOI: https://doi.org/10.1007/978-981-15-2961-0_9

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