Collection

Photoacoustic imaging

Photoacoustic imaging (PAI), also termed optoacoustic imaging (OAI), is a novel imaging modality that can visualize optical contrasts of tissues at high spatial resolution and centimetre-scale imaging depth. By detecting light-induced pressure waves of both endogenous chromophores and exogenous contrast agents, PAI augments bedside ultrasound with functional and molecular information. The potential of PAI for visualization and quantification of inflammation, vascularization and oxygenation has been shown for diagnosis and evaluating disease activity in multiple indications, including auto-immune diseases, cardiovascular diseases and cancer. With a growing availability of clinical imaging systems, co-development of technology innovators and imaging specialists is vital. More importantly, for working towards clinical implementation clinicians have a key role to identify the correct clinical indication with the most urgent unmet clinical maximising the potential of PAI. As molecular imaging community, we should embrace clinical translation of this promising imaging technique. In this collection, we welcome colleagues to contribute (preclinical and) clinical work on PAI facilitating the uptake in the clinical routine.

Editors

  • Ferdinand Knieling

    Dr. Ferdinand Knieling, a clinician-scientist at University Hospital Erlangen, specializes in translating novel imaging modalities to clinical use. Previously at Stanford University, his lab focuses on light- and sound-based imaging, particularly in chronic inflammatory and rare degenerative diseases. Dr. Knieling's pioneering work in multispectral optoacoustic tomography (MSOT) promises enhanced disease monitoring and treatment evaluation, marking significant strides in bridging research and clinical practice.

  • Schelto Kruijff

    Prof. Schelto Kruijff, a Surgical Oncologist and Endocrine Surgeon at the UMCG focuses on optical imaging for cancer surgery. After earning his PhD in 2011, he pursued fellowships in Sydney and hepato-biliary surgery. His research focuses on the use of photoacoustic imaging and fluorescence imaging to interrogate cellular and molecular functions to create precision cancer surgery aiming to reduce complications and side effects, while at the same time increasing treatment effectivity.

  • Jasper Vonk

    Dr. Jasper Vonk is a resident at the Department of Radiology & Nuclear Medicine and Molecular Imaging at University Medical Center Groningen. As a clinician scientist, his research focuses on translating novel molecular imaging techniques to early-phase clinical studies. His main interest is periprocedural use optical/phoacoustic imaging to improve the efficiency of diagnostic and therapeutic procedures, particularly in oncological care.

Articles (2 in this collection)