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Lung Transplantation

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Pediatric Surgery

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Abstract

Lung transplantation is the only effective treatment for children with end-stage lung disease or pulmonary vascular disease, in which all medical therapies have been exhausted. Cystic fibrosis is the most common indication. Pulmonary hypertension has become a much less common indication, as medical therapy for this has improved substantially over the past decade. An emerging indication is congenital abnormalities in surfactant production and/or metabolism. Although there has been some improvement in outcomes since the onset of lung transplantation, 5-year mortality still hovers around 50%. The limiting factors in successful outcome are donor availability, early graft failure, infection, and bronchiolitis obliterans.

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Authors and Affiliations

  1. Saint Louis University School of Medicine, Saint Louis, MO, USA

    Charles B. Huddleston

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  1. Charles B. Huddleston
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Correspondence to Charles B. Huddleston .

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  1. Our Lady’s Children's Hospital, National Children’s Research Centre, Dublin, Ireland

    Prem Puri

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Huddleston, C.B. (2020). Lung Transplantation. In: Puri, P. (eds) Pediatric Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38482-0_137-1

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  • DOI: https://doi.org/10.1007/978-3-642-38482-0_137-1

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  • Print ISBN: 978-3-642-38482-0

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