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Long-Term Outcomes in Newborn Surgery

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Pediatric Surgery

Abstract

During the last decades, the mortality of patients with congenital defects and malformation complexes has continued to decrease. This development is attributed to technical advances and improved neonatology and pediatric intensive care. For pediatric surgeons, the final outcome measure of repaired congenital defects or acquired neonatal surgical problems is the functional outcome in an adult patient. Unfortunately, a significant percentage of survivors have permanent morbidities and long-term handicaps. Many of these abnormalities are carried on to adulthood, with often significant impact on the quality of life. This chapter highlights the long-term data for congenital diaphragmatic hernia, esophageal atresia, Hirschsprung’s disease, and anorectal malformations with regard to all relevant functional aspects.

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References

  • Bai Y, Chen H, Hao J, et al. Long-term outcome and quality of life after the Swenson procedure for Hirschsprung’s disease. J Pediatr Surg. 2002;37:639–42.

    Article  PubMed  Google Scholar 

  • Baillie CT, Kenny SE, Rintala RJ, et al. Long-term outcome and colonic motility after the Duhamel procedure for Hirschsprung’s disease. J Pediatr Surg. 1999;34:325–9.

    Article  CAS  PubMed  Google Scholar 

  • Beek FJA, Boemers TML, Witkamp TD, et al. Spine evaluation in children with ARM. Pediatr Radiol. 1995;25:S28–32.

    Article  PubMed  Google Scholar 

  • Conway SJ, Craigie RJ, Cooper LH, et al. Early adult outcome of the Duhamel procedure for left-sided Hirschsprung disease – a prospective serial assessment study. J Pediatr Surg. 2007;42:1429–32.

    Article  PubMed  Google Scholar 

  • D’Antiga L, Goulet O. Intestinal failure in children: the European view. J Pediatr Gastroenterol Nutr. 2013;56:118–26.

    Article  PubMed  Google Scholar 

  • Danzer E, Gerdes M, D’Agostino JA, Partridge EA, Hoffman-Craven CH, Bernbaum J, Rintoul NE NE, Flake AW, Adzick NS, Hedrick HL. Preschool neurological assessment in congenital diaphragmatic hernia survivors: outcome and perinatal factors associated with neurodevelopmental impairment. Early Hum Dev. 2013;89:393–400.

    Article  PubMed  Google Scholar 

  • de Vries PA, Peña A. Posterior sagittal anorectoplasty. J Pediatr Surg. 1982;17:638–43.

    Article  Google Scholar 

  • Diseth TH, Emblem R. Somatic function, mental health and psychosocial adjustment of adolescents with anorectal anomalies. J Pediatr Surg. 1996;31:638–43.

    Article  CAS  PubMed  Google Scholar 

  • Diseth TH, Bjornland K, Novik TS, et al. Bowel function, mental health, and psychosocial function in adolescents with Hirschsprung’s disease. Arch Dis Child. 1997;76:100–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Escobar MA, Grosfeld JL, West KW, et al. Long-term outcomes in total colonic aganglionosis: a 32-year experience. J Pediatr Surg. 2005;40:955–61.

    Article  PubMed  Google Scholar 

  • Eypasch E, Williams JI, Wood-Dauphinee S, et al. Gastrointestinal quality of life index: development, validation, and application of a new instrument. Br J Surg. 1995;82:216–22.

    Article  CAS  PubMed  Google Scholar 

  • Gallo G, Zwaveling S, Groen H, Van der Zee D, Hulscher J. Long-gap esophageal atresia: a meta-analysis of jejunal interposition, colon interposition, and gastric pull-up. Eur J Pediatr Surg. 2012;22:420–5.

    Article  PubMed  Google Scholar 

  • Goulet O, Ruemmele F. Causes and management of intestinal failure in children. Gastroenterology. 2006;130:S16–28.

    Article  CAS  PubMed  Google Scholar 

  • Goulet O, Ruemmele F, Lacaille F, Colomb V. Irreversible intestinal failure. J Pediatr Gastroenterol Nutr. 2004;38:250–69.

    Article  PubMed  Google Scholar 

  • Grano C, Aminoff D, Lucidi F, Violani C. Long-term disease-specific quality of life in adult anorectal malformation patients. J Pediatr Surg. 2011;46:691–8.

    Article  PubMed  Google Scholar 

  • Grano C, Aminoff D, Lucidi F, Violani C. Long-term disease-specific quality of life in children and adolescent patients with ARM. J Pediatr Surg. 2012;47:1317–22.

    Article  PubMed  Google Scholar 

  • Gutierrez IM, Kang KH, Jaksic T. Neonatal short bowel syndrome. Semin Fetal Neonatal Med. 2011;16:157–63.

    Article  PubMed  Google Scholar 

  • Hall R, Fleming S, Gysler M, et al. The genital tract in female children with imperforate anus. Am J Obstet Gynecol. 1985;151:169–71.

    Article  CAS  PubMed  Google Scholar 

  • Hartman EE, Oort FJ, Aronson DC, et al. Critical factors affecting quality of life of adult patients with ARM of Hirschsprung’s disease. Am J Gastroenterol. 2004a;99:907–13.

    Article  PubMed  Google Scholar 

  • Hartman EE, Oort FJ, Sprangers MA, et al. Factors affecting quality of life of children and adolescents with anorectal malformations of Hirschsprung’s disease. JPGN. 2008;47:463–7.

    PubMed  Google Scholar 

  • Hashish MS, Dawoud HH, Hirschl RB, et al. Long-term functional outcome and quality of life in patients with high imperforate anus. J Pediatr Surg. 2010;45(1):224–30.

    Article  PubMed  Google Scholar 

  • Hassett S, Snell S, Hughes-Thomas A, Holmes K. 10-year outcome of children born with anorectal malformation, treated by posterior sagittal anorectoplasty, assessed according to the Krickenbeck classification. J Pediatr Surg. 2009;44:399–403.

    Article  PubMed  Google Scholar 

  • Hassink EA, Rieu PN, Severijnen RS, et al. Are adults content or continent after repair for high anal atresia? A long-term follow-up study in patients 18 years of age and older. Ann Surg. 1993;218:196–200.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hassink EA, Rieu PN, Brugman AT, et al. Quality of life after operatively corrected high anorectal malformation. A long-term follow-up study in patients 18 years of age and older. J Pediatr Surg. 1994;29:773–6.

    Article  CAS  PubMed  Google Scholar 

  • Hayward MJ, Kharasch V, Sheils C,Friedman S, Dunleavy M-J, Utter S, Zurakowski D, Jennings R, Wilson JM. Predicting inadequate long-term lung development in children with congenital diaphragmatic hernia: an analysis of longitudinal changes in ventilation and perfusion J Pediatr Surg 2007;42:112– 116.

    Article  PubMed  Google Scholar 

  • Heikkinen M, Rintala RJ, Louhimo I. Bowel function and quality of life in adult patients with operated Hirschsprung’s disease. Pediatr Surg Int. 1995;10:342–4.

    Article  Google Scholar 

  • Heikkinen M, Rintala R, Luukkonen P. Long-term anal sphincter performance after surgery for Hirschsprung’s disease. J Pediatr Surg. 1997;32:1443–6.

    Article  CAS  PubMed  Google Scholar 

  • Holschneider AM. Elektromanometrie des Enddarms. Munich/Wien/Baltimore: Urban & Schwarzenberg; 1983. p. 213–8.

    Google Scholar 

  • Holschneider A, Hutson J, Pena A, et al. Preliminary report on the international conference for the development of standards for the treatment of anorectal malformations. J Pediatr Surg. 2005;40:1521–6.

    Article  PubMed  Google Scholar 

  • Ieiri S, Nakatsuji T, Akiyoshi J, et al. Long-term outcomes and quality of life of Hirschsprung disease in adolescents who have reached 18 years or older – a 47-year single institute experience. J Pediatr Surg. 2010;45:2398–402.

    Article  PubMed  Google Scholar 

  • Iwai N, Degichi E, Kimura O, et al. Social quality of life for adult patients with anorectal malformations. J Pediatr Surg. 2007;42:313–7.

    Article  PubMed  Google Scholar 

  • Jarvi K, Koivusalo A, Rintala RJ, Pakarinen MP. Anorectal manometry with reference to operative rectal biopsy for the diagnosis/exclusion of Hirschsprung’s disease in children under 1 year of age. Int J Color Dis. 2009;24:451–4.

    Article  Google Scholar 

  • Jarvi K, Laitakari E, Koivusalo A, Rintala RJ, Pakarinen MP. Bowel function and gastrointestinal quality of life among adults operated for Hirschsprung disease during childhood. A population-based study. Ann Surg. 2010;252:977–81.

    Article  PubMed  Google Scholar 

  • Jayasekera CS, Desmond PV, Holmes JA, Kitson M, Taylor AC. Cluster of 4 cases of esophageal squamous cell cancer developing in adults with surgically corrected esophageal atresia – time for screening to start. J Pediatr Surg. 2012;47:646–51.

    Article  PubMed  Google Scholar 

  • Karkowski J, Pollock WF, Landon CW. Imperforate anus. Eighteen to thirty year follow-up study. Am J Surg. 1973;126:141–7.

    Article  CAS  PubMed  Google Scholar 

  • Kiesewetter WB, Chang JHT. Imperforate anus: a five to thirty year follow-up perspective. Prog Pediatr Surg. 1977;10:110–20.

    Google Scholar 

  • Killelea BK, Lazar EL, Vitale MG. Principles of outcome analysis. In: Stringer MD, Oldham KT, Mouriquand PDE, editors. Pediatric surgery and urology. Chapter 2. 2nd ed. Cambridge: Cambridge University Press; 2006. p. 17–28.

    Chapter  Google Scholar 

  • Koivusalo A, Pakarinen M, Rintala RJ, Lindahl H. Does postoperative pH monitoring predict complicated gastroesophageal reflux in patients with esophageal atresia? Pediatr Surg Int. 2004;20:670–4.

    Article  CAS  PubMed  Google Scholar 

  • Koivusalo A, Pakarinen M, Vanamo K, Lindahl H, Rintala RJ. Health-related quality of life in adults after repair of congenital diaphragmatic defects – a questionnaire study. J Pediatr Surg. 2005a;40:1376–81.

    Article  PubMed  Google Scholar 

  • Koivusalo A, Pakarinen MP, Turunen P, Saarikoski H, Lindahl H, Rintala RJ. Health-related quality of life in adult patients with esophageal atresia – a questionnaire study. J Pediatr Surg. 2005b;40:307–12.

    Article  PubMed  Google Scholar 

  • Koivusalo A, Pakarinen MP, Rintala RJ. The cumulative incidence of significant gastrooesophageal reflux in patients with oesophageal atresia with a distal fistula – a systematic clinical, pH-metric, and endoscopic follow-up study. J Pediatr Surg. 2007;42:370–4.

    Article  PubMed  Google Scholar 

  • Koivusalo AI, Mikko P, Pakarinen MP, Lindahl HG, Rintala RJ. The cumulative incidence of significant gastroesophageal reflux in patients with congenital diaphragmatic hernia – a systematic clinical, pH-metric, and endoscopic follow-up study. J Pediatr Surg. 2008a;43:279–82.

    Article  PubMed  Google Scholar 

  • Koivusalo AI, Pakarinen MP, Pauniaho SL, Rintala RJ. Antegrade continence enema in the treatment of congenital fecal incontinence beyond childhood. Dis Colon Rectum. 2008b;51:1605–10.

    Article  CAS  PubMed  Google Scholar 

  • Koivusalo AI, Pakarinen MP, Rintala RJ. Modern outcomes of oesophageal atresia: single centre experience over the last twenty years. J Pediatr Surg. 2013;48:297–303.

    Article  PubMed  Google Scholar 

  • Koivusalo AI, Pakarinen MP, Lindahl HG, Rintala RJ. Endoscopic surveillance after repair of oesophageal atresia: longitudinal study in 209 patients. J Pediatr Gastroenterol Nutr. 2016;62(4):562–6.

    Article  PubMed  Google Scholar 

  • Konuma K, Ikawa H, Kohno M, et al. Sexual problems in male patients older than 20 years with anorectal malformations. J Pediatr Surg. 2006;41:306–9.

    Article  PubMed  Google Scholar 

  • Kurvinen A, Nissinen MJ, Gylling H, Miettinen TA, Lampela H, Koivusalo AI, Rintala RJ, Pakarinen MP. Effects of long-term parenteral nutrition on serum lipids, plant sterols, cholesterol metabolism and liver histology in pediatric intestinal failure. J Pediatr Gastroenterol Nutr. 2011;53:440–6.

    CAS  PubMed  Google Scholar 

  • Kurvinen A, Nissinen MJ, Andersson S, Korhonen P, Ruuska T, Taimisto T, Kalliomäki M, Lehtonen L, Sankilampi U, Arikoski P, Saarela T, Miettinen TA, Gylling H, Pakarinen MP. Parenteral plant sterols and intestinal failure associated liver disease in neonates: a prospective nationwide study. J Pediatr Gastroenterol Nutr. 2012;54:803–11.

    Article  CAS  PubMed  Google Scholar 

  • Kyrklund K, Koivusalo A, Rintala RJ, Pakarinen MP. Evaluation of bowel function and fecal continence in 594 Finnish individuals aged 4 to 26 years. Dis Colon Rectum. 2012;55(6):671–6.

    Article  PubMed  Google Scholar 

  • Kyrklund K, Taskinen S, Rintala RJ, Pakarinen MP. Sexual Function, Fertility and Quality of Life after Modern Treatment of Anorectal Malformations. J Urol. 2016;196(6):1741–6.

    Article  PubMed  Google Scholar 

  • Langemeijer RATM, Molenaar JC. Continence after posterior sagittal anorectoplasty. J Pediatr Surg. 1991;26:587–90.

    Article  CAS  PubMed  Google Scholar 

  • Levitt MA, Patel M, Rodriguez G, et al. The tethered spinal cord in patients with anorectal malformations. J Pediatr Surg. 1997;32:462–8.

    Article  CAS  PubMed  Google Scholar 

  • Levitt MA, Stein DM, Pena A. Gynecologic concerns in the treatment of teenagers with cloaca. J Pediatr Surg. 1998;33:188–93.

    Article  CAS  PubMed  Google Scholar 

  • Lindahl H, Rintala R, Sariola H, Louhimo I. Cervical Barrett’s esophagus: a common complication of gastric tube reconstruction. J Pediatr Surg. 1990;25:446–8.

    Article  CAS  PubMed  Google Scholar 

  • Lindahl H, Rintala R, Sariola H, Louhimo I. Long-term endoscopic and flow cytometric follow-up of colon interposition. J Pediatr Surg. 1992;27:859–61.

    Article  CAS  PubMed  Google Scholar 

  • Louhimo I, Lindahl H. Esophageal atresia: primary results of 500 consecutively treated patients. J Pediatr Surg. 1983;18:217–29.

    Article  CAS  PubMed  Google Scholar 

  • Mäkitie O, Heikkinen M, Kaitila I, Rintala R. Hirschsprung’s disease in cartilage-hair hypoplasia has poor prognosis. J Pediatr Surg. 2002;37:1585–8.

    Article  PubMed  Google Scholar 

  • Malmström K, Lohi J, Lindahl H, et al. Longitudinal follow-up of bronchial inflammation, respiratory symptoms, and pulmonary function in adolescents after repair of esophageal atresia with tracheoesophageal fistula. J Pediatr. 2008;153:396–401.

    Article  PubMed  Google Scholar 

  • Malone PS, Ransley PG, Kiely EM. Preliminary report: the antegrade continence enema. Lancet. 1990;336:1217–8.

    Article  CAS  PubMed  Google Scholar 

  • Matley PJ, Cywes S, Berg A, et al. A 20-year follow-up of children born with vestibular anus. Pediatr Surg Int. 1990;5:37–40.

    Article  Google Scholar 

  • Metts JC III, Kotkin L, Kasper S, et al. Genital malformations and coexistent urinary tract and spinal anomalies in patients with imperforate anus. J Urol. 1997;158:1298–300.

    Article  PubMed  Google Scholar 

  • Moore SW, Albertyn R, Cywes S. Clinical outcome and long-term quality of life after surgical correction of Hirschsprung’s disease. J Pediatr Surg. 1996;31:1496–502.

    Article  CAS  PubMed  Google Scholar 

  • Moya FR, Thomas VL, Romaguera J, Mysore MR, Maberry M, Bernard A, Freund M. Fetal lung maturation in congenital diaphragmatic hernia. Am J Obstet Gynecol. 1995;173:1401–5.

    Article  CAS  PubMed  Google Scholar 

  • Muratore CS, Utter S, Jaksic T, Lund DP, Wilson JM. Nutritional morbidity in survivors of congenital diaphragmatic hernia. J Pediatr Surg. 2001;36:1171–6.

    Article  CAS  PubMed  Google Scholar 

  • Mutanen A, Mäkitie O, Pakarinen MP. Risk of metabolic bone disease is increased both during and after weaning off parenteral nutrition in pediatric intestinal failure. Horm Res Paediatr. 2013a;25:227–35.

    Article  CAS  Google Scholar 

  • Mutanen A, Lohi J, Heikkilä P, Koivusalo A, Rintala R, Pakarinen MP. Persistent abnormal liver fibrosis after weaning off parenteral nutrition in pediatric intestinal failure. Hepatology. 2013b; doi:10.1002/hep.26360. [Epub ahead of print]

    PubMed  Google Scholar 

  • Neuvonen MI, Kyrklund K, Rintala RJ, Pakarinen MP. Bowel function and quality of life after transanal endorectal pull-through for Hirschsprung disease: controlled outcomes up to adulthood. Ann Surg. 2017 Mar;265(3):622–9.

    Article  PubMed  Google Scholar 

  • Nixon HH, Puri P. The results of treatment of anorectal anomalies: a thirteen to twenty year follow-up. J Pediatr Surg. 1977b;12:27–3790.

    Article  CAS  PubMed  Google Scholar 

  • Olieman JF, Penning C, Poley MJ, Utens E, Hop W, Tibboel D. Impact of infantile short bowel syndrome on long-term health-related quality of life: a cross sectional study. J Pediatr Surg. 2012;47:1309–16.

    Article  PubMed  Google Scholar 

  • Oliemen JF, Penning C, Spoel M, Ijsseltijn H, van den Hoonaard TL, Excher JC, Bax NM, Tibboel D. Long-term impact of infantile short bowel syndrome on nutritional status and growth. Br J Nutr. 2012;107:1489–97.

    Article  CAS  Google Scholar 

  • Ong NT, Beasley SW. Long-term functional results after perineal surgery for low anorectal anomalies. Pediatr Surg Int. 1990;5:238–40.

    Google Scholar 

  • Pakarinen MP, Rintala RJ, Koivusalo A, Heikkinen M, Lindahl H, Pukkala E. Increased incidence of medullary thyroid carcinoma in patients treated for Hirschsprung’s disease. J Pediatr Surg. 2005;40:1532–4.

    Article  PubMed  Google Scholar 

  • Pakarinen MP, Koivusalo AI, Rintala RJ. Outcomes of intestinal failure – a comparison between children with short bowel and dysmotile intestine. J Pediatr Surg. 2009a;44:2139–44.

    Article  PubMed  Google Scholar 

  • Pakarinen MP, Kurvinen A, Gylling H, Miettinen TA, Pesonen M, Kallio M, Koivusalo AI, Nissinen MJ. Cholesterol metabolism in pediatric short bowel syndrome after weaning off parenteral nutrition. Dig Liver Dis. 2010;42:554–9.

    Article  CAS  PubMed  Google Scholar 

  • Pakarinen MP, Kurvinen A, Koivusalo AI, Iber T, Rintala RJ. Long-term controlled outcomes after autologous intestinal reconstruction surgery in treatment of severe short bowel syndrome. J Pediatr Surg. 2013a;48:339–44.

    Article  PubMed  Google Scholar 

  • Pakarinen MP, Kurvinen A, Koivusalo AI, Makisalo H, Jalanko H, Rintala RJ. Surgical treatment and outcomes of severe pediatric intestinal motility disorders requiring parenteral nutrition. J Pediatr Surg. 2013b;48:333–8.

    Article  PubMed  Google Scholar 

  • Pena A. Anorectal malformations. Semin Pediatr Surg. 1995;4:35–47.

    CAS  PubMed  Google Scholar 

  • Pena A, Hong A. Advances in the management of anorectal malformations. Am J Surg. 2000;180:370–6.

    Article  CAS  PubMed  Google Scholar 

  • Pichler J, Chomtho S, Fewtrell M, Macdonald S, Hill SM. Growth and bone health in pediatric intestinal failure patients receiving long-term parenteral nutrition. Am J Clin Nutr. 2013;97(6):1260–9.

    Article  CAS  PubMed  Google Scholar 

  • Poley MJ, Stolk EA, Tibboel D, Molenaar JC, Busschbach JJ. Short term and long term health related quality of life after congenital anorectal malformations and congenital diaphragmatic hernia. Arch Dis Child. 2004;89:836–41.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rangel SJ, Lawal TA, Bischoff A, et al. The appendix as a conduit for antegrade continence enemas in patients with anorectal malformations: lessons learned from 163 cases treated over 18 years. J Pediatr Surg. 2011;46:1236–42.

    Article  PubMed  Google Scholar 

  • Reding R, De Goyet J d V, Gosseye S, et al. Hirschsprung’s disease: a 20-year experience. J Pediatr Surg. 1997;32:1221–5.

    Article  CAS  PubMed  Google Scholar 

  • Rintala RJ. Congenital cloaca: long-term follow-up results with emphasis on outcomes beyond childhood. Semin Pediatr Surg. 2016;25(2):112–6.

    Article  PubMed  Google Scholar 

  • Rintala R, Lindahl H. Is normal bowel function possible after repair of intermediate and high anorectal malformations. J Pediatr Surg. 1995;30:491–4.

    Article  CAS  PubMed  Google Scholar 

  • Rintala RJ, Lindahl H. PSARP is superior to sacroperineal/sacroabdominoperineal pull-through – a long term follow-up study in males with high anorectal anomalies. J Pediatr Surg. 1999;34:334–7.

    Article  CAS  PubMed  Google Scholar 

  • Rintala RJ, Pakarinen M. Hirschsprung’s disease. In: Stringer M, Oldham KT, Mouriquand PD, editors. Pediatric surgery and urology. Long-term outcomes. Cambridge: Cambridge University Press; 2006. p. 385–400.

    Chapter  Google Scholar 

  • Rintala RJ, Pakarinen MP. Outcome of anorectal malformations and Hirschsprung’s disease beyond childhood. Semin Pediatr Surg. 2010;19:160–7.

    Article  PubMed  Google Scholar 

  • Rintala R, Lindahl H, Louhimo I. Anorectal malformations – results of treatment and long term follow-up of 208 patients. Pediatr Surg Int. 1991;6:36–41.

    Article  Google Scholar 

  • Rintala R, Mildh L, Lindahl H. Fecal continence and quality of life in adult patients with an operated low anorectal malformation. J Pediatr Surg. 1992;27:902–5.

    Article  CAS  PubMed  Google Scholar 

  • Rintala R, Mildh L, Lindahl H. Fecal continence and quality of life in adult patients with an operated high or intermediate anorectal malformation. J Pediatr Surg. 1994;29:777–80.

    Article  CAS  PubMed  Google Scholar 

  • Rintala RJ, Lindahl HG, Rasanen M. Do children with repaired low anorectal malformations have normal bowel function? J Pediatr Surg. 1997;32:823–6.

    Article  CAS  PubMed  Google Scholar 

  • Rivosecchi M, Lucchetti MC, De Gennaro M, et al. Spinal dysraphism detected by magnetic resonance imaging in patients with anorectal anomalies: incidence and clinical significance. J Pediatr Surg. 1995;30:488–90.

    Article  CAS  PubMed  Google Scholar 

  • Ruttenstock E, Puri P. A meta-analysis of clinical outcome in patients with total intestinal aganglionosis. Pediatr Surg Int. 2009;25:833–9.

    Article  PubMed  Google Scholar 

  • Salvia G, Guarino A, Terrin G, Cascioli C, Plaudetto R, Indrio F, Lega L, Stronati M, Corvaglia L, Tagliabue P, De Curtis M. Neonatal onset intestinal failure: an Italian multicenter study. J Pediatr. 2008;153:674–6.

    Article  PubMed  Google Scholar 

  • Sanchez SE, McAteer JP, Goldin AB, Horslen S, Huebner CE, Javid PJ. Health-related quality of life in children with intestinal failure. J Pediatr Gastroenterol Nutr. 2013;57(3):330–4.

    Article  PubMed  Google Scholar 

  • Sato S, Shirane R, Yoshimoto T. Evaluation of tethered cord syndrome associated with anorectal malformations. Neurosurgery. 1993;32:125–7.

    Google Scholar 

  • Sistonen SJ, Koivusalo A, Lindahl H, Pukkala E, Rintala RJ, Pakarinen MP. Cancer after repair of esophageal atresia: population-based long-term follow-up. J Pediatr Surg. 2008;43:602–5.

    Article  PubMed  Google Scholar 

  • Sistonen SJ, Helenius I, Peltonen J, Sarna S, Rintala RJ, Pakarinen MP. Natural history of spinal anomalies and scoliosis associated with esophageal atresia. Pediatrics. 2009;124:e1198–204.

    Article  PubMed  Google Scholar 

  • Sistonen SJ, Koivusalo A, Nieminen U, Lindahl H, Lohi J, Kero M, Kärkkäinen PA, Färkkilä MA, Sarna S, Rintala RJ, Pakarinen MP. Esophageal morbidity and function in adults with repaired esophageal atresia with tracheoesophageal fistula: a population-based long-term follow-up. Ann Surg. 2010a;251:1167–73.

    Article  PubMed  Google Scholar 

  • Sistonen S, Malmberg P, Malmström K, Haahtela T, Sarna S, Rintala RJ, Pakarinen MP. Repaired oesophageal atresia: respiratory morbidity and pulmonary function in adults. Eur Respir J. 2010b;36:1106–12.

    Article  CAS  PubMed  Google Scholar 

  • Spoel M, Meeussen C, Gischler SJ, Hopb WJC, Bax NMA, Wijnen RMH, Tibboel D, de Jongste JC, IJsselstijn H. Respiratory morbidity and growth after open thoracotomy or thoracoscopic repair of esophageal atresia. J Pediatr Surg. 2012;47:1975–83.

    Article  PubMed  Google Scholar 

  • Spoel M, van der Cammen-van Zijp M, Hop W, Tibboel D, de Jongste JC, IJsselstijn H. Lung function in young adults with congenital diaphragmatic hernia, a longitudinal evaluation. Pediatr Pulmonol. 2013;48:130–7.

    Article  PubMed  Google Scholar 

  • Stege G, Fenton A, Jaffray B. Nihilism in the 1990s: the true mortality of congenital diaphragmatic hernia. Pediatrics. 2003;112:532–5.

    Article  PubMed  Google Scholar 

  • Stephens FD, Smith ED. Ano-rectal malformations in children. Chicago: Year Book Medical Publishers; 1971.

    Google Scholar 

  • Stephens FD, Smith ED. Classification, identification and assessment of surgical treatment of anorectal anomalies. Pediatr Surg Int. 1986;1:200–5.

    Article  Google Scholar 

  • Steven M, Fyfe AHB, Raine PAM, Watt I. Esophageal adenocarcinoma: a long-term complication of congenital diaphragmatic hernia? J Pediatr Surg. 2007;42:E1–3.

    Article  PubMed  Google Scholar 

  • Taskinen S, Valanne L, Rintala R. Effect of spinal cord abnormalities on the function of the lower urinary tract in patients with anorectal abnormalities. J Urol. 2002;168:1147–9.

    Article  PubMed  Google Scholar 

  • Taylor I, Duthie HL, Zachary RB. Anal continence following surgery for imperforate anus. J Pediatr Surg. 1973;8:497–503.

    Article  CAS  PubMed  Google Scholar 

  • Templeton JM, Ditesheim JA. High imperforate anus – quantitative result of long-term fecal continence. J Pediatr Surg. 1985;20:645–52.

    Article  PubMed  Google Scholar 

  • Trusler GA, Wilkinson RH. Imperforate anus: a review of 147 cases. Can J Surg. 1962;5:269–77.

    CAS  PubMed  Google Scholar 

  • Tuuha SE, Aziz D, Drake J, et al. Is surgery necessary for asymptomatic tethered cord in anorectal malformation patients? J Pediatr Surg. 2004;39:773–7.

    Article  PubMed  Google Scholar 

  • van den Hout L, Reiss I, Felix JF, Hop WC, Lally PA, Lally KP, Tibboel D. Risk factors for chronic lung disease and mortality in newborns with congenital diaphragmatic hernia. Neonatology. 2010;98:370–80.

    Article  PubMed  Google Scholar 

  • Vanamo K, Rintala RJ, Sovijärvi A, Jääskeläinen J, Lindahl H, Louhimo I. Long-term pulmonary sequelae in survivors of congenital diaphragmatic defects. J Pediatr Surg. 1996a;131:1096–100.

    Article  Google Scholar 

  • Vanamo K, Rintala RJ, Lindahl H, Louhimo I. Long-term gastrointestinal morbidity in patients with congenital diaphragmatic defects. J Pediatr Surg. 1996b;31:551–4.

    Article  CAS  PubMed  Google Scholar 

  • Vanamo K, Peltonen J, Rintala R, Lindahl H, Jääskeläinen J, Louhimo I. Chest wall and spinal deformities in adults with congenital diaphragmatic defects. J Pediatr Surg. 1996c;31:851–4.

    Article  CAS  PubMed  Google Scholar 

  • Varni JM, Limbers CA, Burwinkle TM. Impaired health-related quality of life in children and adolescents with chronic conditions: a comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQL 4.0 Generic Core Scales. Health Qual Life Outcomes. 2007;5:43–58.

    Article  PubMed  PubMed Central  Google Scholar 

  • Waag KL, Loff S, Zahn K, Ali M, Hien S, Kratz M, Neff W, Schaffelder R, Schaible T. Congenital diaphragmatic hernia: a modern day approach. Semin Pediatr Surg. 2008;17:244–54.

    Article  PubMed  Google Scholar 

  • Wales PW, de Silva N, Kim J, Lecce L, To T, Moore A. Neonatal short bowel syndrome: population-based estimates of incidence and mortality rates. J Pediatr Surg. 2004;39:690–5.

    Article  PubMed  Google Scholar 

  • Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30:473–83.

    Article  PubMed  Google Scholar 

  • Warne SA, Wilcox DT, Creichton S, et al. Long term gynecological outcome of patients with persistent cloaca. J Urol. 2003;170:1493–6.

    Article  CAS  PubMed  Google Scholar 

  • Wildhaber BE, Teitelbaum DH, Coran AG. Total colonic Hirschsprung’s disease: a 28-year experience. J Pediatr Surg. 2005;40:203–7.

    Article  PubMed  Google Scholar 

  • Yeung CK, Kiely EM. Low anorectal anomalies: a critical appraisal. Pediatr Surg Int. 1991;6:333–5.

    Google Scholar 

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Authors and Affiliations

  1. Department of Pediatric Surgery, Children’s Hospital, Helsinki University Central Hospital, University of Helsinki, P O Box 281, FIN-00029 HUS, Helsinki, Finland

    Risto J. Rintala, Mikko P. Pakarinen & Antti Koivusalo

Authors
  1. Risto J. Rintala
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  2. Mikko P. Pakarinen
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  3. Antti Koivusalo
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Correspondence to Risto J. Rintala .

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  1. Our Lady’s Children's Hospital, National Children’s Research Centre, Dublin, Ireland

    Prem Puri

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Rintala, R.J., Pakarinen, M.P., Koivusalo, A. (2017). Long-Term Outcomes in Newborn Surgery. In: Puri, P. (eds) Pediatric Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38482-0_89-1

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  • DOI: https://doi.org/10.1007/978-3-642-38482-0_89-1

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