Zusammenfassung
Nach Auftreten zweier epileptischer Anfälle oder eines Anfalls bei Vorliegen bildgebender oder elektroenzephalografischer Risikofaktoren für weitere Anfälle besteht die Indikation zur medikamentösen Anfallsprophylaxe. Die Pharmakotherapie von Epilepsien erzielt bei zwei von drei Patienten eine anhaltende Anfallskontrolle. Moderne Antiepileptika ermöglichen auch in Kombination eine gut verträgliche und interaktionsarme Behandlung ohne negative Langzeitbehandlungsfolgen. Bei sich abzeichnender Pharmakoresistenz ist eine frühe Vorstellung an Epilepsiezentren zur Diagnosesicherung und/oder Evaluation nichtmedikamentöser Behandlungsoptionen erforderlich.
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Schulze-Bonhage, A. (2020). Epilepsien: Medikamentöse Therapie. In: Berlit, P. (eds) Klinische Neurologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44768-0_119-1
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