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Funikuläre Myelose

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Book cover Klinische Neurologie

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Zusammenfassung

Die funikuläre Myelose ist die spinale Ausprägung eines Vitamin-B12- oder seltener eines Folsäuremangelzustands. Häufigste Ursache ist eine gestörte Resorption von Vitamin B12 bei chronisch atrophischer Gastritis mit Intrinsic-Factor-Mangel. In erster Linie kommt es zu einer symmetrischen Demyelinisierung der Hinterstränge und Pyramidenbahnen. Wichtigste Begleiterkrankung ist eine makrozytäre Anämie. Die funikuläre Myelose ist eine behandelbare Erkrankung; in den meisten Fällen ist eine lebenslange Substitutionstherapie notwendig.

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Literatur

Zitierte Literatur

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Author information

Authors and Affiliations

  1. Lüneburg, Deutschland

    Bettina Ende-Henningsen

Authors
  1. Bettina Ende-Henningsen
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Correspondence to Bettina Ende-Henningsen .

Editor information

Editors and Affiliations

  1. Essen, Germany

    Peter Berlit

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Ende-Henningsen, B. (2018). Funikuläre Myelose. In: Berlit, P. (eds) Klinische Neurologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44768-0_72-1

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  • DOI: https://doi.org/10.1007/978-3-662-44768-0_72-1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-44768-0

  • Online ISBN: 978-3-662-44768-0

  • eBook Packages: Springer Referenz Medizin

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