Skip to main content
SpringerLink
Log in
Book cover

The Uveitis Atlas pp 1–5Cite as

Bilateral Diffuse Uveal Melanocytic Proliferation (BDUMP)

  • Living reference work entry
  • First Online:

  • 248 Accesses

Abstract

Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic syndrome characterized by multiple subretinal, round, red patches in the retinal pigment epithelium; hyperfluorescence on fluorescein angiography; multiple elevated pigmented and nonpigmented uveal melanocytic tumors with diffuse uveal tract thickening; exudative retinal detachments; and rapid cataract development leading to progressive loss of vision. BDUMP is predictive of an occult or undiagnosed systemic malignancies and a marker for poor prognosis. The index chapter describes an illustrative case of BDUMP with multimodal imaging.

This is a preview of subscription content, log in via an institution.

Suggested Reading

  • Klemp K, Kiilgaard JF, Heegaard S, Nørgaard T, Andersen MK, Prause JU. Bilateral diffuse uveal melanocytic proliferation: case report and literature review. Acta Ophthalmol. 2017;95(5):439–45.

    Article  PubMed  Google Scholar 

  • Mittal R, Cherepanoff S, Thornton S, Kalirai H, Damato B, Coupland SE. Bilateral diffuse uveal melanocytic proliferation: molecular genetic analysis of a case and review of the literature. Ocul Oncol Pathol. 2015;2(2):94–9.

    Article  PubMed  PubMed Central  Google Scholar 

  • Pefkianaki M, Agrawal R, Desai P, Pavesio C, Sagoo MS. Bilateral diffuse uveal melanocytic proliferation (BDUMP) associated with B-cell lymphoma: report of a rare case. BMC Cancer. 2015;15:23.

    Article  PubMed  PubMed Central  Google Scholar 

  • Saito W, Kase S, Yoshida K, Ohguro H, Yokoi M, Iwaki H, Ohno S. Bilateral diffuse uveal melanocytic proliferation in a patient with cancer-associated retinopathy. Am J Ophthalmol. 2005;140(5):942–5.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA

    Rohan Bir Singh

  2. Advanced Eye Center, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

    Aniruddha Agarwal, Kanika Aggarwal & Vishali Gupta

  3. National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore

    Rupesh Agrawal

  4. Department of Medical Retina, Moorfields Eye Hospital NHS Foundation Trust, London, UK

    Rupesh Agrawal & Mandeep Sagoo

  5. UCL Institute of Ophthalmology, London, UK

    Mandeep Sagoo

Authors
  1. Rohan Bir Singh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Aniruddha Agarwal
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Rupesh Agrawal
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Mandeep Sagoo
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Kanika Aggarwal
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Vishali Gupta
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vishali Gupta .

Editor information

Editors and Affiliations

  1. Advanced Eye Center, PGIMER, Chandigarh, India

    Vishali Gupta

  2. Ophthalmology, University of Nebraska Medical Center, Omaha, Nebraska, USA

    Quan Dong Nguyen

  3. Department of Ophthalmology, Pitié-Salpêtrière University, Paris, France

    Phuc LeHoang

  4. University of Lausanne, Lausanne, Switzerland

    Carl P Herbort Jr.

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer (India) Pvt. Ltd.

About this entry

Cite this entry

Singh, R.B., Agarwal, A., Agrawal, R., Sagoo, M., Aggarwal, K., Gupta, V. (2018). Bilateral Diffuse Uveal Melanocytic Proliferation (BDUMP). In: Gupta, V., Nguyen, Q., LeHoang, P., Herbort Jr., C. (eds) The Uveitis Atlas. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2506-5_105-1

Download citation

  • DOI: https://doi.org/10.1007/978-81-322-2506-5_105-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, New Delhi

  • Print ISBN: 978-81-322-2506-5

  • Online ISBN: 978-81-322-2506-5

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation