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Epidemiology of Child Psychopathology

Major Milestones

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Mental Health and Illness of Children and Adolescents

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Abstract

Background: Child psychiatric epidemiology has developed rapidly from descriptive, cross-sectional studies in the 1960s to the current large-scale prospective cohorts that unravel etiological mechanisms. Objectives: To give an overview of epidemiological studies that have influenced child psychiatry. Methods: A chronological overview of selected major milestone studies to demonstrate the development of child psychiatric epidemiology, with a more in-depth discussion of findings and methodological issues exemplified in one cohort, the Generation R Study

This chapter is an update and extension of Verhulst, F.C. & Tiemeier, H. Eur Child Adolesc Psychiatry (2015) 24: 607. https://doi.org/10.1007/s00787-015-0681-9.

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References

  • Achenbach TM (2009) The Achenbach system of empirically based assessment (ASEBA): development, findings, and applications. University of Vermont, Research Center for Children, Youth, and Families, Burlington

    Google Scholar 

  • Achenbach TM, Edelbrock CS (1981) Behavioral problems and competencies reported by parents of normal and disturbed children aged four through sixteen. Monogr Soc Res Child Dev 46:6, serial nr 188

    Article  Google Scholar 

  • Achenbach TM, Rescorla LA (2007) Multicultural understanding of child and adolescent psychopathology. Guildford, New York

    Google Scholar 

  • Achenbach TM, Rescorla LA, Ivanova MY (2012) International epidemiology of child and adolescent psychopathology I: diagnoses, dimensions, and conceptual issues. J Am Acad Child Adolesc Psychiatry 51:1261–1272

    Article  PubMed  Google Scholar 

  • Andersen AN, Olson J (2011) The Danish National Birth Cohort: selected scientific contributions within perinatal epidemiology and future perspectives. Scand J Public Health 39(Suppl 7):115–120

    Article  PubMed  Google Scholar 

  • Angold A, Costello EJ, Erkanli A, Worthman CM (1999) Pubertal changes in hormone levels and depression in girls. Psychol Med 29:1043–1053

    Article  CAS  PubMed  Google Scholar 

  • Arseneault L, Cannon M, Poulton R, Murray R, Caspi A, Moffitt T (2002) Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study. BMJ 325(23):2012–2013

    Google Scholar 

  • Barker DJ (1995) Fetal origins of coronary heart disease. BMJ 311:171–174

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Barrios YV, Gelaye B, Zhong Q, Nicolaidis C, Rondon MB, Garcia PJ, Sanchez PA, Sanchez SE, Williams MA (2015) Association of childhood physical and sexual abuse with intimate partner violence, poor general health and depressive symptoms among pregnant women. PLoS One. https://doi.org/10.1371/journal.pone.0116609

  • Bath SC, Steer CD, Golding J, Emmett P, Rayman MP (2013) Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon longitudinal study of parents and children (ALSPAC). Lancet 382:331–337

    Article  CAS  PubMed  Google Scholar 

  • Belsky J (2001) Developmental risks (still) associated with early child care. J Child Psychol Psychiatry 42:845–859

    Article  CAS  PubMed  Google Scholar 

  • Belsky J, Pluess M (2009) Beyond diathesis stress: differential susceptibility to environmental influences. Psychol Bull 135:885–908

    Article  PubMed  Google Scholar 

  • Belsky J, Vandell DL, Burchinal M, Clarke-Stewart KA, McCartney K, Owen MT, The NICHD Early Child Care Research Network (2007) Are there long-term effects of early child care? Child Dev 78:681–701

    Article  PubMed  Google Scholar 

  • Bolhuis K, Kushner SA, Yayniz S et al (2018) Maternal and paternal cannabis use during pregnancy and the risk of psychotic-like experiences in the offspring. Schizophr Res 202:322–327

    Article  PubMed  Google Scholar 

  • Brent BK, Thermenos HW, Keshavan MS, Seidman LJ (2013) Gray matter alterations in schizophrenia high-risk youth and early-onset schizophrenia: a review of structural MRI findings. Child Adolesc Psychiatr Clin N Am 22:689–714

    Article  PubMed  PubMed Central  Google Scholar 

  • Brion M, Zeegers M, Jaddoe V et al (2011) Intrauterine effects of maternal prepregnancy overweight of child cognition and behaviour in 2 cohorts. Pediatrics 127:202–211

    Article  Google Scholar 

  • Casey BM, Thom EA, Peaceman AM, Varner MW, Sorokin Y, Hirtz DG, Reddy UM et al (2017) Treatment of subclinical hypothyroidism or hypothyroxinemia in pregnancy. N Engl J Med 376:815–825

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Casey BJ, Cannonier T, Conley MI, Cohen AO, Barch DM, Heitzeg MM, Soules ME, Teslovich T, Dellarco DV, Garavan H, Orr CA, Wager TD, Banich MT, Speer NK, Sutherland MT, Riedel MC, Dick AS, Bjork JM, Thomas KM, Chaarani B, Mejia MH, Hagler DJ Jr, Daniela Cornejo M, Sicat CS, Harms MP, Dosenbach NUF, Rosenberg M, Earl E, Bartsch H, Watts R, Polimeni JR, Kuperman JM, Fair DA, Dale AM, Imaging Acquisition Workgroup ABCD (2018) The adolescent brain cognitive development (ABCD) study: imaging acquisition across 21 sites. Dev Cogn Neurosci 32:43–54

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Caspi A, Moffitt TE (2001) Childhood predictors differentiate life-course persistent and adolescence-limited antisocial pathways among males and females. Dev Psychopathol 13:355–375

    Article  PubMed  Google Scholar 

  • Caspi A, Moffitt TE, Newman DL, Silva PA (1996) Behavioral observations at age 3 years predict adult psychiatric disorders: longitudinal evidence from a birth cohort. Arch Gen Psychiatry 53:1033–1039

    Article  CAS  PubMed  Google Scholar 

  • Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW, Taylor A, Poulton R (2002) Role of genotype in the cycle of violence in maltreated children. Science 297:851–854

    Article  CAS  PubMed  Google Scholar 

  • Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, McClay J, Mill J, Martin J, Braithwaite A, Poulton R (2003) Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301:386–389

    Article  CAS  PubMed  Google Scholar 

  • Caspi A, Williams B, Kim-Cohen J et al (2007) Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. Proc Natl Acad Sci 104:18860–18865

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cederblad M (1968) A child psychiatric study on Sudanese Arab children. Acta Psychiatr Scand 44(Suppl 200), 230

    Google Scholar 

  • Cederblad M, Rahmin SI (1986) Effects of rapid urbanization on child behaviour and health in a part of Khartoum, Sudan: I socioeconomic changes 1965–1980. Soc Sci Med 22:713–721

    Article  CAS  PubMed  Google Scholar 

  • Costello EJ, Angold A, Burns B et al (1996) The Great Smokey Mountains study of youth: goals, designs, methods, and the prevalence of DSM-III disorders. Arch Gen Psychiatry 53:1129–1136

    Article  CAS  PubMed  Google Scholar 

  • Costello EJ, Compton SN, Keeler G, Angold A (2003) Relationships between poverty and psychopathology. JAMA 290:2023–2029

    Article  CAS  PubMed  Google Scholar 

  • Demontis D, Walters RK, Martin J et al (2019) Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nat Genet 51:63–75

    Article  CAS  PubMed  Google Scholar 

  • D’Onofrio BMD, Van Hullea CA, Goodnight JA, Rathouza PJ, Lahey BB (2011) Is maternal smoking during pregnancy a causal environmental risk factor for adolescent antisocial behavior? Testing etiological theories and assumptions. Psychol Med 42:1535–1545

    Article  PubMed  PubMed Central  Google Scholar 

  • Duncan LE (2013) Paying attention to all results, positive and negative. J Am Acad Child Adolesc Psychiatry 52:462–456

    Article  PubMed  Google Scholar 

  • Eaves LJ, Silberg JL, Meyer JM, Maes HH, Simonoff E, Pickles A, Rutter M, Reynolds CA, Heath AC, Truett KR, Neale MC, Erikson MT, Loeber R, Hewitt JK (1997) Genetics and developmental psychopathology: 2 the main effects of genes and environment on behavioral problems in the Virginia twin study of adolescent behavioral development. J Child Psychol Psychiatry 38:965–980

    Article  CAS  PubMed  Google Scholar 

  • El Marroun H, Tiemeier H, Steegers EAP et al (2009) Intrauterine cannabis exposure affects fetal growth trajectories: the Generation R study. J Am Acad Child Adolesc Psychiatry 48:1173–1181

    Article  PubMed  Google Scholar 

  • El Marroun H, Jaddoe VW, Hudziak JJ et al (2012) Maternal use of selective serotonin reuptake inhibitors, fetal growth, and risk of adverse birth outcomes. Arch Gen Psychiatry 69:706–714

    Article  PubMed  Google Scholar 

  • El Marroun H, Tiemeier H, IHA F et al (2016) Prenatal cannabis and tobacco exposure in relation to brain morphology: a prospective neuroimaging study in young children. Biol Psychiatry 79:971–979

    Article  PubMed  CAS  Google Scholar 

  • El Marroun H, Bolhuis K, Franken IHA, Jaddoe VWV, Hillegers MH, Lahey BB, Tiemeier H (2019) Preconception and prenatal cannabis use and the risk of behavioural and emotional problems in the offspring; a multi-informant prospective longitudinal study. Int J Epidemiol 48:287–296

    Article  PubMed  Google Scholar 

  • Fergusson DM, Horwood LJ (2001) The Christchurch child development study: review of findings on child mental health. Aust N Z J Psychiatry 35:287–296

    Article  CAS  PubMed  Google Scholar 

  • Fergusson DM, Horwood LJ, Shannon FT, Lawton JM (1989) The Christchurch child development study: a review of epidemiological findings. Paediatr Perinat Epidemiol 3:302–325

    Article  CAS  PubMed  Google Scholar 

  • Fergusson DM, Horwood LJ, Lynskey MT (1996) Child sexual abuse and psychiatric disorder in young adulthood: II psychiatric outcomes of child sexual abuse. J Am Acad Child Adolesc Psychiatry 35:1365–1374

    Article  CAS  PubMed  Google Scholar 

  • Fergusson DM, Woodward LJ, Horwood LJ (2000) Risk factors and life processes associated with the onset of suicidal behaviour during adolescence and early adulthood. Psychol Med 30:23–39

    Article  CAS  PubMed  Google Scholar 

  • Fergusson DM, McLeod GF, Horwood LJ (2014) Parental separation/divorce in childhood and partnership outcomes at age 30. J Child Psychol Psychiatry 55:352–360

    Article  PubMed  Google Scholar 

  • Gale CR, Martyn CN (2004) Birth weight and later weight of depression in a national birth cohort. Br J Psychiatry 184:28–33

    Article  PubMed  Google Scholar 

  • Garavan H, Bartsch H, Conway K, Decastro A, Goldstein RZ, Heeringa S, Jernigan T, Potter A, Thompson W, Zahs D (2018) Recruiting the ABCD sample: design considerations and procedures. Dev Cogn Neurosci 32:16–22

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Golding J, Pembrey M, Jones R, ALSPAC Study Team (2001) ALSPAC – the Avon longitudinal study of parents and children: I study methodology. Paediatr Perinat Epidemiol 15:74–87

    Article  CAS  PubMed  Google Scholar 

  • Greene N, Greenland S, Olsen J, Nohr EA (2011) Estimating bias from loss to follow-up in the Danish national birth cohort. Epidemiology 22:815–822

    PubMed  Google Scholar 

  • Gyllenberg D, Sourander A, Surcel H-M, Hinkka-Yli-Salomäki S, McKeague IW, Brown AS (2016) Hypothyroxinemia during gestation and offspring schizophrenia in a national birth cohort. Biol Psychiatry 79:962–970

    Article  CAS  PubMed  Google Scholar 

  • Hallal PC, Bertoldi AD, Domingues MR, Freitas da Silveira M, Demarco FF, M da Silva IC, Barros FC, Victora CG, Bassani DG (2018) Cohort profile: the 2015 Pelotas (Brazil) birth cohort study. Int J Epidemiol 47:1048–1048h

    Article  PubMed  Google Scholar 

  • Henrichs J, Schenk JJ, Schmidt H et al (2009) Fetal size in mid- and late pregnancy is related to infant alertness: the Generation R study. Dev Psychobiol 51:119–130

    Article  PubMed  Google Scholar 

  • Hewitt JK, Silberg JL, Rutter M, Simonoff E, Meyer JM, Maes HH, Pickles A, Neale MC, Loeber R, Erickson MT, Kendler KS, Heath AC, Truett KR, Reynolds CA, Eaves LJ (1997) Genetics and developmental psychopathology: 1 phenotypic assessment in the Virginia twin study of adolescent behavioral development. J Child Psychol Psychiatry 38:943–963

    Article  CAS  PubMed  Google Scholar 

  • Hibbeln JR, Davis JM, Steer C, Emmett P, Rogers I, Williams C, Golding J (2007) Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study. Lancet 369:578–585

    Article  PubMed  Google Scholar 

  • Ioannidis JP (2008) Interpretation of tests of heterogeneity and bias in meta-analysis. J Eval Clin Pract 14:951–957

    Article  PubMed  Google Scholar 

  • Jaddoe VW, van Duijn CM, van der Heijden AJ et al (2010) The Generation R study: design and cohort update 2010. Eur J Epidemiol 25:823–841

    Article  PubMed  PubMed Central  Google Scholar 

  • Jansen PW, Raat H, Mackenbach JP et al (2009) Socioeconomic inequalities in infant temperament. The Generation R study. Soc Psychiatry Psychiatr Epidemiol 44:87–95

    Article  PubMed  Google Scholar 

  • Jansen TA, Korevaar TIM, Mulder TA, White T, Muetzel RL, Peeters RP, Tiemeier H (2019) Maternal thyroid function during pregnancy and child brain morphology: a time window-specific analysis of a prospective cohort. Lancet Diabetes Endocrinol 7:629–637

    Article  CAS  PubMed  Google Scholar 

  • Jones P (1997) The early origins of schizophrenia. Br Med Bull 53:135–155

    Article  CAS  PubMed  Google Scholar 

  • Kan K, Dolan CV, Nivard MG, Middeldorp CM, van Beijsterveldt CEM, Willemsen G, Boomsma DI (2013) Genetic and environmental stability in attention problems across the lifespan: evidence from the Netherlands twin register. J Am Acad Child Adolesc Psychiatry 52:12–25

    Article  PubMed  Google Scholar 

  • Korevaar TI, Muetzel R, Medici M et al (2016) Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study. Lancet Diabetes Endocrinol 4:35–43

    Article  CAS  PubMed  Google Scholar 

  • Lahti J, Räikkönen K, Kajantie E, Heinonen K, Pesonen AK, Järvenpää AL, Strandberg T (2006) Small body size at birth and behavioural symptoms of ADHD in children aged five to six years. J Child Psychol Psychiatry 47:1167–1174

    Article  CAS  PubMed  Google Scholar 

  • Lampi KM, Banerjee PN, Gissler M et al (2011) Finnish prenatal study of autism and autism spectrum disorders (FIPS-A): overview and design. J Autism Dev Disord 41:1090–1096

    Article  PubMed  Google Scholar 

  • Lampi KM, Hinkka-Yli-Salomäki S, Lehti V et al (2013) Parental age and risk of autism spectrum disorders in a Finnish national birth cohort. J Autism Dev Disord 43:2526–2535

    Article  PubMed  Google Scholar 

  • Lapouse L, Monk MA (1958) An epidemiological study of behavior characteristics in children. Am J Public Health 48:1134–1144

    Article  CAS  Google Scholar 

  • Levey EJ, Rondon MB, Sanchez S et al (2019) Suicide risk assessment: examining transitions in suicidal behaviors among pregnant women in Perú. Arch Womens Ment Health 22:65–73

    Article  PubMed  Google Scholar 

  • Lichtenstein P, Tuvblad C, Larsson H, Carlström E (2007) The Swedish twin study of child and adolescent development: the TCHAD-study. Twin Res Hum Genet 10:67–73

    Article  PubMed  Google Scholar 

  • Loeber R, Menting B, Lynam D, Moffitt TE, Stouthamer-Loeber M, Stallings R, Farrington DP, Pardini D (2012) Findings from the Pittsburgh youth study: cognitive impulsivity and intelligence as predictors of the age-crime curve. J Am Acad Child Adolesc Psychiatry 51:1136–1149

    Article  PubMed  Google Scholar 

  • Magnus P, Irgens LM, Haug K, Nystad W, Skjaerven R, Stoltenberg C, MoBa Study Group (2006) Cohort profile: the Norwegian mother and child cohort study (MoBa). Int J Epidemiol 35:1146–1150

    Article  PubMed  Google Scholar 

  • Maughan B, Messer J, Collishaw S, Pickles A, Snowling M, Yule W, Rutter M (2009) Persistence of literacy problems: spelling in adolescence and at mid-life. J Child Psychol Psychiatry 50:893–901

    Article  CAS  PubMed  Google Scholar 

  • Medici M, Timmermans S, Visser W, de Muinck Keizer-Schrama SMPF, Jaddoe VWW, Hofman A, Hooijkaas H, de Rijke YB, Tiemeier H, Bongers-Schokking JJ, Visser TJ, Peeters RP, Steegers EAP (2013) Maternal thyroid hormone parameters during early pregnancy and birth weight: the Generation R study. J Clin Endocrinol Metab 98:59–66

    Article  CAS  PubMed  Google Scholar 

  • Middeldorp CM, Felix JF, Mahajan A, McCarthy MI, Early Growth Genetics (EGG) Consortium (2019) The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects. Eur J Epidemiol 34:279–300

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Modesto T, Tiemeier H, Peeters RP et al (2015) Maternal mild thyroid hormone insufficiency in early pregnancy and attention-deficit/hyperactivity disorder symptoms in children. JAMA Pediatr 169:838–845

    Article  PubMed  Google Scholar 

  • Muetzel RL, Blanken LME, van der Ende J, El Marroun H, Shaw P, Sudre G et al (2017) Tracking brain development and dimensional psychiatric symptoms in children: a longitudinal population-based neuroimaging study. Am J Psychiatry 175:54–62

    Article  PubMed  Google Scholar 

  • Nagin D, Tremblay RE (1999) Trajectories of boys’ physical aggression, opposition, and hyperactivity on the path to physically violent and nonviolent juvenile delinquency. Child Dev 70:1181–1196

    Article  CAS  PubMed  Google Scholar 

  • NICHD Early Child Care Research Network (1997) The effects of infant child care on infant-mother attachment. Child Dev 68:860–879

    Article  Google Scholar 

  • Nohr E, Frydenberg M, Henriksen TB, Olsen J (2006) Does low participation in cohort studies induce bias? Epidemiology 17:413–418

    Article  PubMed  Google Scholar 

  • Nymberg C, Jia T, Ruggeri B, Schumann G (2013) Analytical strategies for large imaging genetic datasets: experiences from the IMAGEN study. Ann N Y Acad Sci 1282:92–106

    Article  CAS  PubMed  Google Scholar 

  • Odgers CL, Moffitt TE, Broadbent JM, Dickson N, Hancox RJ, Harrington H, Poulton R, Sears MR, Thomson WM, Caspi A (2008) Female and male antisocial trajectories: from childhood origins to adult outcomes. Dev Psychopathol 20:673–716

    Article  PubMed  Google Scholar 

  • Pitzer M, Esser G, Schmidt MH, Laucht M (2009) Temperamental predictors of externalizing problems among boys and girls: a longitudinal study in a high-risk sample from ages 3 months to 15 years. Eur Arch Psychiatry Clin Neurosci 259:445–458

    Article  PubMed  Google Scholar 

  • Plomin R, DeFries JC, McClearn GE (1980) Behavioral genetics: a primer. WH Freeman and Company, San Francisco

    Google Scholar 

  • Power C (1992) A review of child health in the 1958 birth cohort: national child development study. Paediatr Perinat Epidemiol 6:81–110

    Article  CAS  PubMed  Google Scholar 

  • Rahmin SI, Cederblad M (1984) Effects of rapid urbanization on child behaviour and health in a part of Khartoum, Sudan. J Child Psychol Psychiatry 25:629–641

    Article  Google Scholar 

  • Ramchandani PG, Stein A, Hotopf M, Wiles NJ, ALSPAC Study Team (2006) Early parental and child predictors of recurrent abdominal pain at school age: results of a large population-based study. J Am Acad Child Adolesc Psychiatry 45:729–736

    Article  PubMed  Google Scholar 

  • Richter LM, Victora CG, Hallal PC, Adair LS, Bhargava SK, CHD F, Lee N, Martorell R, Norris SA, Sachdev HS, Stein AD, the COHORTS Group (2011) Cohort profile: the consortium of health oriented research in transitioning societies. Int J Epidemiol 41:621–626

    Article  PubMed  PubMed Central  Google Scholar 

  • Rijlaarsdam J, Stevens GWJM, van der Ende J et al (2013) Economic disadvantage and young children’s behavioral and emotional problems: mechanisms of risk. J Abnorm Child Psychol 41:125–137

    Article  PubMed  Google Scholar 

  • Ringoot AP, Tiemeier H, Jaddoe VWV, So P, Hofman A, Verhulst FC, Jansen PW (2015) Parental depression and child wellbeing: young children’s self-reports helped addressing biases in parent reports. J Clin Epidemiol 68:928–938

    Article  PubMed  Google Scholar 

  • Rogler LH (1989) The meaning of culturally sensitive research in mental health. Am J Psychiatry 146:296–303

    Article  CAS  PubMed  Google Scholar 

  • Roman GC, Ghassabian A, Bongers-Schokking JJ et al (2013) Association of gestational maternal hypothyroxinemia and increased autism risk. Ann Neurol 74:733–742

    Article  CAS  PubMed  Google Scholar 

  • Roza SJ, Verburg BO, Jaddoe WV et al (2007) Effects of maternal smoking in pregnancy on prenatal brain development. The Generation R study. Eur J Neurosci 25:611–617

    Article  PubMed  Google Scholar 

  • Roza S, van Lier P, Jaddoe V et al (2008) Intrauterine growth and infant temperamental difficulties: the Generation R study. J Am Acad Child Adolesc Psychiatry 47:264–272

    Article  PubMed  Google Scholar 

  • Roza S, Verhulst FC, Jaddoe VWV et al (2009) Maternal smoking during pregnancy and child behavior problems: the Generation R study. Int J Epidemiol 38:680–689

    Article  PubMed  Google Scholar 

  • Rutter M, Tizard JR, Whitmore K (1970) Education, health and behaviour. Longman, London

    Google Scholar 

  • Rutter M, Tizard J, Yule W, Graham P, Whitmore K (1976) Research report: Isle of Wight studies, 1964–1974. Psychol Med 6:313–332

    Article  CAS  PubMed  Google Scholar 

  • Serdarevic F, Ghassabian A, van Batenburg-Eddes T, Tahirovic E, White T, Jaddoe VWV, Verhulst FC, Tiemeier H (2017) Infant neuromotor development and childhood problem behavior. Pediatrics 140:e20170884

    Article  PubMed  Google Scholar 

  • Serdarevic F, Jansen PR, Ghassabian A, White T, Jaddoe VW, Posthuma D, Tiemeier H (2018) Association of genetic risk for schizophrenia and bipolar disorder with infant neuromotor development. JAMA Psychiat 75(1):96–98

    Article  Google Scholar 

  • Serdarevic F, Tiemeier H, Jansen PR, Alemany S, Xerxa Y, Neumann A et al (2020) Polygenic risk scores for developmental disorders, neuromotor functioning during infancy, and autistic traits in childhood. Biol Psychiatry 87:132–138

    Article  CAS  PubMed  Google Scholar 

  • Shaheen SO, Newson RB, Smith GD, Henderson AJ (2010) Prenatal paracetamol exposure and asthma: further evidence against confounding. Int J Epidemiol 39:790–794

    Article  PubMed  Google Scholar 

  • Shaw P, Rabin C (2009) New insights into attention-deficit/ hyperactivity disorder using structural neuroimaging. Curr Psychiatr Rep 11:393–398

    Article  Google Scholar 

  • Silva PA, Stanton WR (1996) Child to adult: the Dunedin multidisciplinary health and development study. Oxford University Press, Oxford

    Google Scholar 

  • Silva LM, Jansen PW, Steegers EAP et al (2010) Mother’s educational level and fetal growth: the genesis of health inequalities. Int J Epidemiol 39:1250–1261

    Article  PubMed  Google Scholar 

  • Smyke AT, Zeanah CH Jr, Fox NA, Nelson CA 3rd. (2009) A new model of foster care for young children: the Bucharest early intervention project. Child Adolesc Psychiatr Clin N Am 18:721–3482

    Article  PubMed  Google Scholar 

  • Surén P, Roth C, Bresnahan M, Haugen M, Hornig M, Hirtz D, Lie KK, Lipkin WI, Magnus P, Reichborn-Kjennerud T, Schjølberg S, Davey Smith G, Øyen AS, Susser E, Stoltenberg C (2013a) Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. JAMA 309:570–577

    Article  PubMed  PubMed Central  Google Scholar 

  • Surén P, Stoltenberg C, Bresnahan M, Hirtz D, Lie KK, Lipkin WI, Magnus P, Reichborn-Kjennerud T, Schjølberg S, Susser E, Oyen AS, Li L, Hornig M (2013b) Early growth patterns in children with autism. Epidemiology 24:60–670

    Article  Google Scholar 

  • Thompsom L, Kemp J, Wilson P, Pritchett R, Minnis H, Toms L, Puckering C, Law J, Gillberg C (2010) What have birth cohort studies asked about genetic, pre- and perinatal exposures and child and adolescent onset mental health outcomes? A systematic review. Eur Child Adolesc Psychiatry 19:1–15

    Article  Google Scholar 

  • Tiemeier H, Velders F, Szekely E et al (2012) The Generation R study: a review of design, findings to date, and a study of the 5-HTTLPR by environmental interaction from fetal life onward. J Am Acad Child Adolesc Psychiatry 51:1119–1135

    Article  PubMed  Google Scholar 

  • Timonen-Soivio L, Sourander A, Malm H et al (2015) The association between autism spectrum disorders and congenital anomalies by organ systems in a Finnish national birth cohort. J Autism Dev Disord 45:3195–3203

    Article  PubMed  Google Scholar 

  • Tremblay RE, Pihl RO, Vitaro F, Dobkin PL (1994) Predicting early onset of male antisocial behavior from preschool behavior. Arch Gen Psychiatry 51:732–739

    Article  CAS  PubMed  Google Scholar 

  • Velders FP, Dieleman G, Henrichs J et al (2011) Prenatal and postnatal psychological symptoms of parents and family functioning: the impact on child emotional and behavioural problems. Eur Child Adolesc Psychiatry 20:341–350

    Article  PubMed  PubMed Central  Google Scholar 

  • Verhulst FC, Tiemeier H (2015) Epidemiology of child psychopathology: major milestones. Eur Child Adolesc Psychiatry 24:607–617

    Article  PubMed  PubMed Central  Google Scholar 

  • Wadsworth MEJ (1991) The imprint of time: childhood history and adult life. Clarendon Press, Oxford

    Google Scholar 

  • Welham J, Isohanni M, Jones P, McGrath J (2009) The antecedents of schizophrenia: a review of birth cohort studies. Schizophr Bull 35:603–623

    Article  PubMed  Google Scholar 

  • Werner EE, Smith RS (1992) Overcoming the odds: high risk children from birth to adulthood. Cornell University Press, London

    Google Scholar 

  • Werner EE, Bierman JM, French FE (1971) The children of Kauai: a longitudinal study from the prenatal period to age ten. University of Hawaii Press, London

    Google Scholar 

  • Wolke D, Waylen A, Samara M, Steer C, Goodman R, Ford T, Lamberts K (2009) Selective drop-out in longitudinal studies and non-biased prediction of behaviour disorders. Br J Psychiatry 195:249–256

    Article  PubMed  PubMed Central  Google Scholar 

  • Zhong QY, Wells A, Rondon MB, Williams MA, Barrios YV, Sanchez SE, Gelaye B (2016) Childhood abuse and suicidal ideation in a cohort of pregnant Peruvian women. Am J Obstet Gynecol 215:501.e1–501.e8

    Article  Google Scholar 

  • Zuccolo L, Lewis SJ, Smith GD et al (2013) Prenatal exposure and offspring cognition and school performance: a ‘Medelian randomization’ natural experiment. Int J Epidemiol 42:1358–1370

    Article  PubMed  PubMed Central  Google Scholar 

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Verhulst, F.C., Tiemeier, H. (2020). Epidemiology of Child Psychopathology. In: Taylor, E., Verhulst, F., Wong, J., Yoshida, K., Nikapota, A. (eds) Mental Health and Illness of Children and Adolescents. Mental Health and Illness Worldwide. Springer, Singapore. https://doi.org/10.1007/978-981-10-0753-8_11-1

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  • Print ISBN: 978-981-10-0753-8

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  • eBook Packages: Springer Reference Behavioral Science and PsychologyReference Module Humanities and Social SciencesReference Module Business, Economics and Social Sciences

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