1. 5-Fluorouracil's cytotoxicity is enhanced both in vitro and in vivo by concomitant treatment with hyperthermia and dipyridamole

   • Yoshihiko Maehara
   • Yoshihisa Sakaguchi
   • Keizo Sugimachi

   Original Articles Pages: 257 - 260

2. Reduced cardiotoxicity and increased cytotoxicity in a novel anthracycline analogue, 4′-amino-3′-hydroxy-doxorubicin

   • Romano Danesi
   • Nunzia Bernardini
   • Mario Del Tacca

   Original Articles Pages: 261 - 265

3. Antitumor effect of KT6124, a novel derivative of protein kinase inhibitor K-252a and its mechanism of action

   • Shiro Akinaga
   • Tadashi Ashizawa
   • Masami Okabe

   Original Articles Pages: 266 - 272

4. In vivo comparative therapeutic study of optimal administration of 5-fluorouracil and cisplatin using a newly established HST-1 human squamous-carcinoma cell line

   • Mika Kuroki
   • Shuji Nakano
   • Yoshiyuki Niho

   Original Articles Pages: 273 - 276

5. O ⁶-Methylguanine-DNA methyltransferase activity and induction of novel immunogenicity in murine tumor cells treated with methylating agents

   • Roberta Bianchi
   • Lorenzo Citti
   • Maria Cristina Fioretti

   Original Articles Pages: 277 - 282

6. Expression of the mdr1 gene in human colorectal carcinomas: relationship with multidrug resistance inferred from analysis of human colorectal carcinoma cell lines

   • Giuseppe Toffoli
   • Alessandra Viel
   • Mauro Boiocchi

   Original Articles Pages: 283 - 289

7. In vitro antineoplastic activity of C7-substituted mitomycin C analogues MC-77 and MC-62 against human breast-cancer cell lines

   • Alem Ghiorghis
   • Abdolhossen Talebian
   • Robert Clarke

   Original Articles Pages: 290 - 296

8. Cellular kinetics of prednimustine versus chlorambucil plus prednisolone in vitro

   • Eugen Musch
   • Mouhamad Malek
   • Eberhard Riedel

   Original Articles Pages: 297 - 304

9. Phase II trial of PALA in combination with 5-fluorouracil in advanced pancreatic cancer

   • Elizabeth Rosyold
   • Russell Schilder
   • Peter J. O'Dwyer

   Original Articles Pages: 305 - 308

10. Long-term studies of cisplatin-induced reductions in porcine renal functional reserve

    • Mike E. C. Robbins
    • Tony Bywaters
    • Elizabeth Whitehouse

    Original Articles Pages: 309 - 315

11. Pharmacokinetics of high-dose etoposide after short-term infusion

    • P. Köhl
    • H. Köppler
    • H. Jungclas

    Original Articles Pages: 316 - 320

12. Phase II study of single-agent etoposide in patients with metastatic squamous-cell carcinoma of the esophagus

    • Andreas Harstrick
    • Carsten Bokemeyer
    • Hansjochen Wilke

    Original Articles Pages: 321 - 322

13. Non-aggressive therapy for chronic myeloid leukaemia in blastic transformation

    • Raymond Liang
    • T. K. Chan
    • David Todd

    Short Communication Pages: 323 - 325

14. Alpha-interferon in combination with 5-fluorouracil and leucovorin in metastatic colorectal cancer: a phase I study

    • C. J. A. Punt
    • P. H. M. de Mulder
    • D. J. Th. Wagener

    Short Communication Pages: 326 - 328

15. Interferon-related cortical blindness

    • Ofer Merimsky
    • Puiu Nisipeanu
    • Samario Chaitchik

    Short Communication Pages: 329 - 330

16. The distribution ofo,p′-DDD (Mitotane) among serum lipoproteins in normo- and hypertriglyceridemia

    • D. O. E. Gebhardt
    • A. J. Moolenaar
    • J. A. Gevers Leuven

    Short Communication Pages: 331 - 334

17. Intrathecal administration of etoposide in the treatment of malignant meningitis: feasibility and pharmacokinetic data

    • Ate van der Gaast
    • Pieter Sonneveld
    • Ted A. W. Splinter

    Short Communication Pages: 335 - 337

18. Meeting announcement

    Announcement Pages: 338 - 338