1. Quantitation of the synergistic interaction of edatrexate and cisplatin in vitro

   • Ting-Chao Chou
   • Queng-Hui Tan
   • Francis M. Sirotnak

   Original Articles Pages: 259 - 264

2. Pharmacokinetics of peptichemio in myeloma patients: release ofm-l-sarcolysin in vivo and in vitro

   • Hans Ehrsson
   • Rolf Lewensohn
   • Bo Johansson

   Original Articles Pages: 265 - 268

3. Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma

   • G. J. Peters
   • J. Lankelma
   • H. M. Pinedo

   Original Articles Pages: 269 - 276

4. Relationship between the melanin content of a human melanoma cell line and its radiosensitivity and uptake of pimonidazole

   • R. El Gamoussi
   • M. D. Threadgill
   • M. Guichard

   Original Articles Pages: 277 - 282

5. Phase I clinical and pharmacology study of 502U83 given as a 24-h continuous intravenous infusion

   • Richard L. Schilsky
   • Mark J. Ratain
   • Richard L. Tuttle

   Original Articles Pages: 283 - 288

6. Correlation of the in vitro cytotoxicity of ethyldeshydroxysparsomycin and cisplatin with the in vivo antitumour activity in murine L1210 leukaemia and two resistant L1210 sublcones

   • H. P. Hofs
   • D. J. T. Wagener
   • H. C. J. Ottenheijm

   Original Articles Pages: 289 - 294

7. Doxorubicin and local hyperthermia in the microcirculation of skeletal muscle

   • Andreas S. Lübbe

   Original Articles Pages: 295 - 300

8. Decreased resistance toN,N-dimethylated anthracyclines in multidrug-resistant Friend erythroleukemia cells

   • András Schaefer
   • Johannes Westendorf
   • Hans Marquardt

   Original Articles Pages: 301 - 307

9. Antitumor activity of the aromatase inhibitor FCE 24928 on DMBA-induced mammary tumors in ovariectomized rats treated with testosterone

   • T. Zaccheo
   • E. di Salle

   Original Articles Pages: 308 - 312

10. Organ distribution and antitumor activity of free and liposomal doxorubicin injected into the hepatic artery

    • Yiyu Zou
    • Isamu Horikoshi
    • Roman Perez-Soler

    Original Articles Pages: 313 - 318

11. Effect of toremifene on antipyrine elimination in the isolated perfused rat liver

    • Lorraine K. Webster
    • Andrew G. Ellis
    • James F. Bishop

    Original Articles Pages: 319 - 323

12. A limited sampling method for estimation of the carboplatin area under the curve

    • Bente T. Sørensen
    • Annette Strömgren
    • Anders Jakobsen

    Original Articles Pages: 324 - 327

13. Pharmacokinetics of 10-ethyl-10-deaza-aminopterin, edatrexate, given weekly for non-small-cell lung cancer

    • Janet M. Hartley
    • Paul W. Nicholson
    • Robert L. Souhami

    Original Articles Pages: 328 - 332

14. Phase I clinical evaluation of [SP-4-3(R)]-[1,1-cyclobutanedicarboxylato(2-)](2-methyl-1,4-butanediamine-N,N ¹) platinum in patients with metastatic solid tumors

    • Richard L. Theriault
    • I. A. Cohen
    • Martin N. Raber

    Original Articles Pages: 333 - 337

15. Phase II study of high-dose ifosfamide in hepatocellular carcinoma

    • J. Lin
    • W. Shiu
    • A. K. C. Li

    Short Communication Pages: 338 - 339

16. Ifosfamide in advanced epidermoid head and neck cancer

    • M. Martín
    • E. Diaz-Rubio
    • S. Dominguez

    Short Communication Pages: 340 - 342