1. Editorial

   • Merrill J. Egorin
   • Herbie Newell

   EditorialNotes Pages: 1 - 1

2. Is body composition an important variable in the pharmacokinetics of anticancer drugs?

   • John J. Reilly
   • Paul Workman

   Review Pages: 3 - 13

3. Factors affecting human autopsy kidney-cortex and kidney-medulla platinum concentrations after cisplatin administration

   • David J. Stewart
   • Corinne Dulberg
   • Rakesh Goel

   Original Articles Pages: 14 - 22

4. Nationwide randomized comparative study of daunorubicin and aclarubicin in combination with behenoyl cytosine arabinoside, 6-mercaptopurine, and prednisolone for previously untreated acute myeloid leukemia

   • Eiichi Nagura
   • Kiyoji Kimura
   • Nobuyuki Hamajima

   Original Articles Pages: 23 - 29

5. Combination of fludarabine and arabinosylcytosine for treatment of chronic lymphocytic leukemia: clinical efficacy and modulation of arabinosylcytosine pharmacology

   • V. Gandhi
   • L. E. Robertson
   • W. Plunkett

   Original Articles Pages: 30 - 36

6. Efficacy of recombinant human granulocyte-macrophage colony-stimulating factor for chemotherapy-induced leukopenia in patients with non-small-cell lung cancer

   • K. Eguchi
   • J. Kabe
   • N. Saijo

   Original Articles Pages: 37 - 43

7. V79 Chinese hamster lung cells resistant to the bis-alkylator bizelesin are multidrug-resistant

   • Robert K. Butryn
   • Kathy S. Smith
   • Bijoy K. Bhuyan

   Original Articles Pages: 44 - 50

8. Comparative cytotoxicity of folate-based inhibitors of thymidylate synthase and 5-fluorouracil ± leucovorin in MGH-U1 cells

   • Charles Erlichman
   • Biserka Mitrovski

   Original Articles Pages: 51 - 56

9. 5-Fluorouracil causes alterations in the pharmacokinetic profile of tauromustine in NMRI mice

   • Simon R. Hill
   • Mike C. Bibby

   Original Articles Pages: 57 - 62

10. Biochemical and antitumor activity of trimidox, a new inhibitor of ribonucleotide reductase

    • Thomas Szekeres
    • Kamran Gharehbaghi
    • Howard L. Elford

    Original Articles Pages: 63 - 66

11. Up-regulation of γ-glutamylcysteine synthetase activity in melphalan-resistant human multiple myeloma cells expressing increased glutathione levels

    • R. Timothy Mulcahy
    • Howard H. Bailey
    • Jerry J. Gipp

    Original Articles Pages: 67 - 71

12. Etoposide, leucovorin, 5-fluorouracil and interferon alpha-2b in elderly gastric cancer patients: a pilot study

    • Stefano Cascinu
    • Anna Fedeli
    • Giuseppina Catalano

    Clinical Trial Report Pages: 72 - 74

13. Weekly 5-fluorouracil and high-dose folinic acid in combination with epidoxorubicin as first-line therapy in advanced breast cancer: a phase II study

    • Herbert Stöger
    • Thomas Bauerhofer
    • Hellmut Samonigg

    Clinical Trial Report Pages: 75 - 78

14. Phase IV trial of daily oral etoposide in the treatment of advanced soft-tissue sarcoma

    • Jonathan D. Licht
    • Rosemary Mazanet
    • Karen H. Antman

    Clinical Trial Report Pages: 79 - 80

15. Dominant expression of multidrug resistance in intraspecific murine lymphoma hybrid cells

    • István Pályi
    • Gizella Turi
    • Mihály Bak

    Short Communication Pages: 81 - 85

16. Decrease in penbutolol protein binding as a consequence of treatment with some alkylating agents

    • Carmelo Aguirre
    • Jose Miguel Rodríguez-Sasiain
    • Rosario Calvo

    Short Communication Pages: 86 - 88