1. Regulatory considerations for preclinical development of anticancer drugs

   • Joseph J. DeGeorge
   • Chang-Ho Ahn
   • Satish C. Tripathi

   ORIGINAL ARTICLE Pages: 173 - 185

2. Abrogated energy-dependent uptake of cisplatin in a cisplatin-resistant subline of the human ovarian cancer cell line IGROV-1

   • Jianguo Ma
   • Marc Maliepaard
   • Jan H. M. Schellens

   ORIGINAL ARTICLE Pages: 186 - 192

3. Augmentation of hepatic doxorubicin extraction with extracorporeal filtration avoids the dose-dependent, nonlinear increase in AUC observed with systemic administration

   • Marc G. Sturgill
   • Dean E. Brenner
   • David A. August

   ORIGINAL ARTICLE Pages: 193 - 200

4. Whole-body disposition and polyglutamate distribution of the GAR formyltransferase inhibitors LY309887 and lometrexol in mice: effect of low-folate diet

   • Lillian L Habeck
   • Sylvia H. Chay
   • Laurane G. Mendelsohn

   ORIGINAL ARTICLE Pages: 201 - 209

5. Alkylphosphocholines induce apoptosis in HL-60 and U-937 leukemic cells

   • Spiro M. Konstantinov
   • Hansjörg Eibl
   • Martin R. Berger

   ORIGINAL ARTICLE Pages: 210 - 216

6. Activity of gemcitabine in non-small-cell lung cancer: results of the Japan gemcitabine group (A) phase II study

   • Minoru Takada
   • Shun-ichi Negoro
   • Masahiro Fukuoka

   ORIGINAL ARTICLE Pages: 217 - 222

7. An inhibitor of glycinamide ribonucleotide formyltransferase is selectively cytotoxic to cells that lack a functional G1 checkpoint

   • Cathy C. Zhang
   • Theodore J. Boritzki
   • Robert C. Jackson

   ORIGINAL ARTICLE Pages: 223 - 228

8. Clinical effects and pharmacokinetics of the fusion protein PIXY321 in children receiving myelosuppressive chemotherapy

   • Wayne L. Furman
   • John H. Rodman
   • William H. Meyer

   ORIGINAL ARTICLE Pages: 229 - 236

9. Characterization of acylfulvene histiospecific toxicity in human tumor cell lines

   • Michael J. Kelner
   • Trevor C. McMorris
   • Raymond Taetle

   ORIGINAL ARTICLE Pages: 237 - 242

10. A combination chemoendocrine therapy of mitoxantrone, doxifluridine, and medroxyprogesterone acetate for anthracycline-resistant advanced breast cancer

    • Yuichi Iino
    • Takao Yokoe
    • Seiichiro Kishi

    ORIGINAL ARTICLE Pages: 243 - 247

11. Sample handling for determination of free platinum in blood after cisplatin exposure

    • Anders Johnsson
    • Henrik Björk
    • Tor Skärby

    SHORT COMMUNICATION Pages: 248 - 251

12. Piperazine derivatives of butyric acid as differentiating agents in human leukemic cells

    • Reynald Gillet
    • P. Jeannesson
    • François Pieri

    SHORT COMMUNICATION Pages: 252 - 255