1. Phase I dose escalation pharmacokinetics of O-(chloroacetylcarbamoyl) fumagillol (TNP-470) and its metabolites in AIDS patients with Kaposi's sarcoma

   • Jeff D. Moore
   • Bruce J. Dezube
   • Jean-Pierre Sommadossi

   ORIGINAL ARTICLE Pages: 173 - 179

2. Feasibility of a novel weekday-on/weekend-off oral UFT schedule as postoperative adjuvant chemotherapy for colorectal cancer

   • Sotaro Sadahiro
   • Shigeru Ohki
   • Hiroyasu Makuuchi

   ORIGINAL ARTICLE Pages: 180 - 184

3. Effect of tamoxifen pretreatment on the pharmacokinetics, metabolism and cardiotoxicity of doxorubicin in female rats

   • Sujata Vaidyanathan
   • Mehdi Boroujerdi

   ORIGINAL ARTICLE Pages: 185 - 192

4. Ara-C differentially affects multiprotein forms of human cell DNA polymerase

   • Philip W. Wills
   • Robert Hickey
   • Linda Malkas

   ORIGINAL ARTICLE Pages: 193 - 203

5. Pretreatment with ranitidine does not reduce the bioavailability of orally administered topotecan

   • Saad Akhtar
   • Robert A. Beckman
   • Jonathan Wright

   ORIGINAL ARTICLE Pages: 204 - 210

6. Modified irinotecan hydrochloride (CPT-11) administration schedule improves induction of delayed-onset diarrhea in rats

   • Akinobu Kurita
   • Shoichi Kado
   • Teruo Yokokura

   ORIGINAL ARTICLE Pages: 211 - 220

7. Cisplatin versus cisplatin combined with piroxicam in a canine model of human invasive urinary bladder cancer

   • Deborah W. Knapp
   • Nita W. Glickman
   • Lawrence T. Glickman

   ORIGINAL ARTICLE Pages: 221 - 226

8. Population pharmacokinetics of pemetrexed disodium (ALIMTA) in patients with cancer

   • D. Ouellet
   • A. P. Periclou
   • R. L. Lalonde

   ORIGINAL ARTICLE Pages: 227 - 234

9. Effect of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on plasma concentration of uridine released from 2′,3′,5′-tri-O-acetyluridine, a prodrug of uridine: relevance to uridine rescue in chemotherapy

   • Osama M. Ashour
   • Fardos N. M. Naguib
   • Mahmoud H. el Kouni

   ORIGINAL ARTICLE Pages: 235 - 240

10. The role of caspase family protease, caspase-3 on cisplatin-induced apoptosis in cisplatin-resistant A431 cell line

    • Hiroshi Mese
    • Akira Sasaki
    • Tomohiro Matsumura

    ORIGINAL ARTICLE Pages: 241 - 245

11. Preclinical oral antitumor activity of BMS-185660, a paclitaxel derivative

    • William C. Rose
    • Francis Y. F. Lee
    • John Kadow

    ORIGINAL ARTICLE Pages: 246 - 250

12. A phase II pharmacodynamic study of pyrazoloacridine in patients with metastatic colorectal cancer

    • Robert Pelley
    • Ram Ganapathi
    • G. Thomas Budd

    SHORT COMMUNICATION Pages: 251 - 254