1. A phase I study of suramin with once- or twice-monthly dosing in patients with advanced cancer

   • Christopher W. Ryan
   • Everett E. Vokes
   • Mark J. Ratain

   Original Article Pages: 1 - 5

2. Phase II study of liposomal annamycin in the treatment of doxorubicin-resistant breast cancer

   • Daniel J. Booser
   • Francisco J. Esteva
   • Gabriel N. Hortobagyi

   Original Article Pages: 6 - 8

3. Rapid biotransformation of satraplatin by human red blood cells in vitro

   • Jocelyn L. Carr
   • Malcolm D. Tingle
   • Mark J. McKeage

   Original Article Pages: 9 - 15

4. A population analysis of the pharmacokinetics of Cremophor EL using nonlinear mixed-effect modelling

   • H. van den Bongard
   • R. Mathôt
   • J. Beijnen

   Original Article Pages: 16 - 24

5. Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor agent in animal model and in patients with impaired renal function

   • Masataka Ikeda
   • Hiroshi Furukawa
   • Takashi Satomi

   Original Article Pages: 25 - 32

6. Leucocyte versus erythrocyte thioguanine nucleotide concentrations in children taking thiopurines for acute lymphoblastic leukaemia

   • D. Lancaster
   • N. Patel
   • J. Lilleyman

   Original Article Pages: 33 - 36

7. Analysis of age, estimated creatinine clearance and pretreatment hematologic parameters as predictors of fludarabine toxicity in patients treated for chronic lymphocytic leukemia: a CALGB (9011) coordinated intergroup study

   • Robert E. Martell
   • Bercedis L. Peterson
   • Herbert I. Hurwitz

   Original Article Pages: 37 - 45

8. Chemotherapeutic agents enhance TRAIL-induced apoptosis in prostate cancer cells

   • A. Munshi
   • T. McDonnell
   • R. Meyn

   Original Article Pages: 46 - 52

9. The effect of keratinocyte growth factor on tumour growth and small intestinal mucositis after chemotherapy in the rat with breast cancer

   • Rachel J. Gibson
   • Dorothy M. Keefe
   • Adrian G. Cummins

   Original Article Pages: 53 - 58

10. Urinary and fecal excretion of topotecan in patients with malignant solid tumours

    • Virginie M. Herben
    • Nadja Schoemaker
    • Jos H. Beijnen

    Original Article Pages: 59 - 64

11. Suicide gene therapy using E. coli β-galactosidase

    • David Farquhar
    • Bih Pan
    • Arly J. Nelson

    Original Article Pages: 65 - 70

12. Structure-activity relationships of alkylphosphocholine derivatives: antineoplastic action on brain tumor cell lines in vitro

    • Verena Jendrossek
    • Kerstin Hammersen
    • Max Lakomek

    Original Article Pages: 71 - 79

13. Pilot study of gemcitabine (10 mg/m² per min) and cisplatin

    • Elizabeth Poplin
    • Al Benson
    • Mary Mulcahy

    Clinical Trial Report Pages: 80 - 83