1. Patupilone (epothilone B, EPO906) and imatinib (STI571, Glivec) in combination display enhanced antitumour activity in vivo against experimental rat C6 glioma

   • T. O’Reilly
   • M. Wartmann
   • P. M. J. McSheehy

   Original Article 26 October 2004 Pages: 307 - 317

   

2. Isolated pelvic perfusion: plasma pharmacokinetics depend primarily on drug dosage and not the type of drug

   • James F. Belliveau
   • Elisabeth Arevalo
   • Harold J. Wanebo

   Original Article 15 January 2005 Pages: 318 - 322

   

3. A possible mechanism for the long-lasting antitumor effect of the macromolecular conjugate DE-310: mediation by cellular uptake and drug release of its active camptothecin analog DX-8951

   • Yusuke Ochi
   • Yoshinobu Shiose
   • Eiji Kumazawa

   Original Article 26 October 2004 Pages: 323 - 332

   

4. Role of glutathione and nucleotide excision repair in modulation of cisplatin activity with O⁶-benzylguanine

   • Melissa L. Fishel
   • Michael P. Gamcsik
   • M. Eileen Dolan

   Original Article 02 October 2004 Pages: 333 - 342

   

5. Endometrial K-ras mutations in postmenopausal breast cancer patients treated with adjuvant tamoxifen or toremifene

   • Mika Wallén
   • Eija Tomás
   • Johanna Mäenpää

   Original Article 20 November 2004 Pages: 343 - 346

6. Interactions of carboxypeptidase G₂ with 6S-leucovorin and 6R-leucovorin in vitro: implications for the application in case of methotrexate intoxications

   • Georg Hempel
   • Rainer Lingg
   • Joachim Boos

   Original Article 21 October 2004 Pages: 347 - 353

   

7. Phase I study of weekly (day 1 and 8) docetaxel in combination with capecitabine in patients with advanced solid malignancies

   • Ramesh K. Ramanathan
   • Sakkaraiappan Ramalingam
   • William C. Zamboni

   Original Article 27 October 2004 Pages: 354 - 360

   

8. Biochemical modulation of cytarabine triphosphate by clofarabine

   • Todd Cooper
   • Mary Ayres
   • Varsha Gandhi

   Original Article 16 October 2004 Pages: 361 - 368

   

9. RETRACTED ARTICLE: Quinoxaline 1,4-dioxides induce G₂/M cell cycle arrest and apoptosis in human colon cancer cells

   • Hala U. Gali-Muhtasib
   • Mona Diab-Assaf
   • Makhluf J. Haddadin

   Original Article 05 November 2004 Pages: 369 - 378

   

10. Imatinib pharmacokinetics in patients with gastrointestinal stromal tumour: a retrospective population pharmacokinetic study over time. EORTC Soft Tissue and Bone Sarcoma Group

    • Ian Judson
    • Peiming Ma
    • Allan van Oosterom

    Original Article 09 December 2004 Pages: 379 - 386

    

11. Does cisplatin (CDDP) function as a modulator of 5-fluorouracil (5-FU) antitumor action? A study based on a clinical trial

    • Satoshi Matsusaka
    • Tomofumi Nagareda
    • Hajime Yamasaki

    Original Article 13 January 2005 Pages: 387 - 392

    

12. Gefitinib (“Iressa”, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells

    • Osamu Kishida
    • Yoshiji Miyazaki
    • Yasuhisa Shinomura

    Original Article 05 October 2004 Pages: 393 - 403

    

13. Bioavailability and pharmacokinetics of the investigational anticancer agent XK469 (NSC 698215) in rats following oral and intravenous administration

    • Ramesh R. Boinpally
    • Sen-Lin Zhou
    • Ralph E. Parchment

    Short Communication 09 December 2004 Pages: 404 - 407

    

14. Acknowledgement to Reviewers 2004

    Acknowledgement to Reviewers 18 February 2005 Pages: 408 - 410