1. Preface

   • Yutaka Ariyoshi
   • Tetsuya Mitsudomi
   • Ryuzo Ueda

   EditorialNotes 05 November 2005 Pages: 1 - 3

2. Function of nuclear sex hormone receptors in gene regulation

   • Shigeaki Kato
   • Takashi Sato
   • Takahiro Matsumoto

   OriginalPaper 05 November 2005 Pages: 4 - 9

   

3. Advanced concepts in estrogen receptor biology and breast cancer endocrine resistance: implicated role of growth factor signaling and estrogen receptor coregulators

   • Rachel Schiff
   • Suleiman A. Massarweh
   • C. Kent Osborne

   OriginalPaper 05 November 2005 Pages: 10 - 20

   

4. Clinical significance of estrogen receptor β in breast cancer

   • Shigehira Saji
   • Makiko Hirose
   • Masakazu Toi

   OriginalPaper 05 November 2005 Pages: 21 - 26

   

5. Estrogen signaling and prediction of endocrine therapy

   • Shin-ichi Hayashi
   • Yuri Yamaguchi

   OriginalPaper 05 November 2005 Pages: 27 - 31

   

6. The use of aromatase inhibitors in adjuvant therapy for early breast cancer

   • Walter Jonat
   • Felix Hilpert
   • Nicolai Maass

   OriginalPaper 05 November 2005 Pages: 32 - 38

   

7. Resistance to endocrine therapy in breast cancer

   • Junichi Kurebayashi

   Original Article 05 November 2005 Pages: 39 - 46

8. Beyond simple castration: targeting the molecular basis of treatment resistance in advanced prostate cancer

   • Martin Gleave
   • Hideaki Miyake
   • Kim Chi

   OriginalPaper 05 November 2005 Pages: 47 - 57

   

9. Hormone treatment for prostate cancer: current issues and future directions

   • Tomohiko Ichikawa
   • Hiroyoshi Suzuki
   • Satoko Kojima

   OriginalPaper 05 November 2005 Pages: 58 - 63

   

10. A self-renewal assay for cancer stem cells

    • Michael F. Clarke

    OriginalPaper 05 November 2005 Pages: 64 - 68

    

11. Chemotherapy for prostate cancer: implementing early systemic therapy to improve outcomes

    • Gary R. MacVicar
    • Maha Hussain

    OriginalPaper 05 November 2005 Pages: 69 - 77

12. Current status of dose-dense chemotherapy for breast cancer

    • Andrew D. Seidman

    OriginalPaper 05 November 2005 Pages: 78 - 83

    

13. Drug resistance in chemotherapy for breast cancer

    • Toshiaki Saeki
    • Takashi Tsuruo
    • Kiyoshiro Nishikawsa

    OriginalPaper 05 November 2005 Pages: 84 - 89

    

14. Translational studies for target-based drugs

    • Kazuto Nishio
    • Tokuzo Arao
    • Nagahiro Saijo

    OriginalPaper 05 November 2005 Pages: 90 - 93

    

15. Trastuzumab: updates and future issues

    • Masakazu Toi
    • Kazumi Horiguchi
    • Louis W. C. Chow

    OriginalPaper 05 November 2005 Pages: 94 - 99