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Verumontanum Mucosal Gland Hyperplasia

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  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

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Definition

Relatively well-circumscribed collection of closely packed glands, typically observed in the verumontanum and adjacent posterior urethra (Gaudin et al. 1995).

Clinical Features

  • Incidence

    Rare. Usually an incidental finding in radical prostatectomy specimens in patients with prostate cancer or benign prostatic hyperplasia. It can also be seen in needle biopsies and TURP specimens.

  • Age

    Usually in the age of prostate cancer or benign prostatic hyperplasia.

  • Sex

    Male.

  • Site

    Verumontanum. It is located in the posterior aspect of the prostatic urethra where the utricle and the ejaculatory ducts empty into the urethra.

  • Treatment

    Not required.

  • Outcome

    Benign.

Microscopy

It is characterized by a microacinar proliferation of uniform, well-circumscribed, closely packed, rounded glands that usually contain lamellated eosinophilic secretions (intraluminal corpora amylacea) and unique orange-red concretions that are commonly fragmented. A basal cell layer is identifiable (Gaudin et al. 1995...

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References and Further Reading

  • Gaudin, P. B., Wheeler, T. M., & Epstein, J. I. (1995). Verumontanum mucosal gland hyperplasia in prostatic needle biopsy specimens: A mimic of low grade prostatic adenocarcinoma. American Journal of Clinical Pathology, 104, 620–626.

    Article  CAS  Google Scholar 

  • Srigley, J. R. (2004). Benign mimickers of prostatic adenocarcinoma. Modern Pathology, 17(3), 328–348.

    Article  Google Scholar 

  • Young, R. H. (1995). Tumor-like lesions of the prostate gland. American Journal of Clinical Pathology, 104(6), 607–610.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Institute of Pathological Anatomy and Histopathology, Polytechnic University of the Marche Region (Ancona), Ancona, Italy

    Alessia Cimadamore, Roberta Mazzucchelli & Rodolfo Montironi

Authors
  1. Alessia Cimadamore
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  2. Roberta Mazzucchelli
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  3. Rodolfo Montironi
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Corresponding author

Correspondence to Rodolfo Montironi .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Cimadamore, A., Mazzucchelli, R., Montironi, R. (2019). Verumontanum Mucosal Gland Hyperplasia. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4996-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4996-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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