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Types of Pancreatic Resections

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Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

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Introduction

Depending on the underlying pathology and its location within the organ, a wide range of surgical techniques for the operative treatment of pancreatic diseases is available. The most common procedures are the resection of the pancreatic head (including the Whipple procedure) and the resection of the pancreatic body/tail, the so-called distal or left pancreatectomy (Kleeff et al. 2016).

Partial Pancreaticoduodenectomy with or Without Pylorus Preservation

Partial pancreaticoduodenectomy (PD) also referred to as the Whipple operation is a complex surgical procedure for the treatment of benign and malignant diseases of the periampullary region. Common indications to perform a PD include malignancies, most importantly pancreatic ductal adenocarcinoma, followed by distal bile duct cholangiocarcinoma, adenocarcinoma of the ampulla of Vateri, and duodenal adenocarcinoma. The periampullary region can give rise to a variety of less common cancers including neuroendocrine tumors and...

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References and Further Reading

  • Almond, M., Roberts, K. J., Hodson, J., et al. (2015). Changing indications for a total pancreatectomy: Perspective over a quarter of a century. HPB, 17, 416–421.

    Article  Google Scholar 

  • Beger, H. G., Schlosser, W., Friess, H. M., et al. (1999). Duodenum-preserving head resection in chronic pancreatitis changes the natural course of the disease: A single-center 26-year experience. Annals of Surgery, 230(4), 512–519. discussion 519–523.

    Article  CAS  Google Scholar 

  • Casadei, R., Monari, F., Buscemi, S., et al. (2010). Total pancreatectomy: Indications, operative technique, and results: A single centre experience and review of literature. Updates in Surgery, 62, 41–46.

    Article  Google Scholar 

  • Diener, M. K., Hüttner, F. J., Kieser, M., Knebel, P., Dörr-Harim, C., Distler, M., Grützmann, R., Wittel, U. A., Schirren, R., Hau, H. M., Kleespies, A., Heidecke, C. D., Tomazic, A., Halloran, C. M., Wilhelm, T. J., Bahra, M., Beckurts, T., Börner, T., Glanemann, M., Steger, U., Treitschke, F., Staib, L., Thelen, K., Bruckner, T., Mihaljevic, A. L., Werner, J., Ulrich, A., Hackert, T., Büchler, M. W., & ChroPac Trial Group. (2017). Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet, 390(10099), 1027–1037.

    Article  Google Scholar 

  • Guerra, F., Giuliani, G., Bencini, L., Bianchi, P. P., & Coratti, A. (2018). Minimally invasive versus open pancreatic enucleation. Systematic review and meta-analysis of surgical outcomes. Journal of Surgical Oncology, 117(7), 1509–1516.

    Article  Google Scholar 

  • Hackert, T., Werner, J., Weitz, J., et al. (2010). Uncinate process first--a novel approach for pancreatic head resection. Langenbeck’s Archives of Surgery, 395(8), 1161–1164.

    Article  Google Scholar 

  • Hartwig, W., Gluth, A., Hinz, U., Bergmann, F., Spronk, P. E., Hackert, T., Werner, J., & Büchler, M. W. (2015). Total pancreatectomy for primary pancreatic neoplasms: Renaissance of an unpopular operation. Annals of Surgery, 261(3), 537–546.

    Article  Google Scholar 

  • Hüttner, F. J., Koessler-Ebs, J., Hackert, T., Ulrich, A., Büchler, M. W., & Diener, M. K. (2015). Meta-analysis of surgical outcome after enucleation versus standard resection for pancreatic neoplasms. The British Journal of Surgery, 102(9), 1026–1036.

    Article  Google Scholar 

  • Keck, T., Wellner, U. F., Bahra, M., Klein, F., Sick, O., Niedergethmann, M., Wilhelm, T. J., Farkas, S. A., Börner, T., Bruns, C., Kleespies, A., Kleeff, J., Mihaljevic, A. L., Uhl, W., Chromik, A., Fendrich, V., Heeger, K., Padberg, W., Hecker, A., Neumann, U. P., Junge, K., Kalff, J. C., Glowka, T. R., Werner, J., Knebel, P., Piso, P., Mayr, M., Izbicki, J., Vashist, Y., Bronsert, P., Bruckner, T., Limprecht, R., Diener, M. K., Rossion, I., Wegener, I., & Hopt, U. T. (2016). Pancreatogastrostomy versus pancreatojejunostomy for RECOnstruction after PANCreatoduodenectomy (RECOPANC, DRKS 00000767): Perioperative and long-term results of a multicenter randomized controlled trial. Annals of Surgery, 263(3), 440–449.

    Article  Google Scholar 

  • Kempeneers, M. A., Issa, Y., Ali, U. A., Baron, R. D., Besselink, M. G., Büchler, M., Erkan, M., Fernandez-Del Castillo, C., Isaji, S., Izbicki, J., Kleeff, J., Laukkarinen, J., Sheel, A. R. G., Shimosegawa, T., Whitcomb, D. C., Windsor, J., Miao, Y., Neoptolemos, J., Boermeester, M. A., & Working group for the International (IAP – APA – JPS – EPC) Consensus Guidelines for Chronic Pancreatitis. (2020). International consensus guidelines for surgery and the timing of intervention in chronic pancreatitis. Pancreatology, 20(2), 149–157.

    Article  CAS  Google Scholar 

  • Klaiber, U., Probst, P., Büchler, M. W., & Hackert, T. (2017). Pylorus preservation pancreatectomy or not. Translational Gastroenterology Hepatology, 2, 100.

    Article  Google Scholar 

  • Kleeff, J., Korc, M., Apte, M., La Vecchia, C., Johnson, C. D., Biankin, A. V., Neale, R. E., Tempero, M., Tuveson, D. A., Hruban, R. H., & Neoptolemos, J. P. (2016). Pancreatic cancer. Nature Reviews. Disease Primers, 2, 16022.

    Article  Google Scholar 

  • Kleeff, J., Whitcomb, D. C., Shimosegawa, T., Esposito, I., Lerch, M. M., Gress, T., Mayerle, J., Drewes, A. M., Rebours, V., Akisik, F., Muñoz, J. E. D., & Neoptolemos, J. P. (2017). Chronic pancreatitis. Nature Reviews. Disease Primers, 3, 17060.

    Article  Google Scholar 

  • Kulu, Y., Schmied, B. M., Werner, J., et al. (2009). Total pancreatectomy for pancreatic cancer: Indications and operative technique. HPB, 11, 469–475.

    Article  Google Scholar 

  • Miao, Y., Lu, Z., Yeo, C. J., Vollmer, C. M., Jr., Fernandez-Del Castillo, C., Ghaneh, P., Halloran, C. M., Kleeff, J., de Rooij, T., Werner, J., Falconi, M., Friess, H., Zeh, H. J., Izbicki, J. R., He, J., Laukkarinen, J., Dejong, C. H., Lillemoe, K. D., Conlon, K., Takaori, K., Gianotti, L., Besselink, M. G., Del Chiaro, M., Montorsi, M., Tanaka, M., Bockhorn, M., Adham, M., Oláh, A., Salvia, R., Shrikhande, S. V., Hackert, T., Shimosegawa, T., Zureikat, A. H., Ceyhan, G. O., Peng, Y., Wang, G., Huang, X., Dervenis, C., Bassi, C., Neoptolemos, J. P., Büchler, M. W., & International Study Group of Pancreatic Surgery (ISGPS). (2020). Management of the pancreatic transection plane after left (distal) pancreatectomy: Expert consensus guidelines by the International Study Group of Pancreatic Surgery (ISGPS). Surgery, 168(1), 72–84.

    Article  Google Scholar 

  • Müller, M. W., Friess, H., Kleeff, J., Hinz, U., Wente, M. N., Paramythiotis, D., Berberat, P. O., Ceyhan, G. O., & Büchler, M. W. (2006). Middle segmental pancreatic resection: An option to treat benign pancreatic body lesions. Annals of Surgery, 244(6), 909–918. discussion 918–20.

    Article  Google Scholar 

  • Schneider, M., Strobel, O., Hackert, T., & Büchler, M. W. (2019). Pancreatic resection for cancer-the Heidelberg technique. Langenbeck’s Archives of Surgery, 404(8), 1017–1022.

    Article  Google Scholar 

  • Shrikhande, S. V., Sivasanker, M., Vollmer, C. M., Friess, H., Besselink, M. G., Fingerhut, A., Yeo, C. J., Fernandez-delCastillo, C., Dervenis, C., Halloran, C., Gouma, D. J., Radenkovic, D., Asbun, H. J., Neoptolemos, J. P., Izbicki, J. R., Lillemoe, K. D., Conlon, K. C., Fernandez-Cruz, L., Montorsi, M., Bockhorn, M., Adham, M., Charnley, R., Carter, R., Hackert, T., Hartwig, W., Miao, Y., Sarr, M., Bassi, C., & Büchler, M. W. (2017). Pancreatic anastomosis after pancreatoduodenectomy: A position statement by the International Study Group of Pancreatic Surgery (ISGPS). Surgery, 161(5), 1221–1234.

    Article  Google Scholar 

  • Strasberg, S. M., Linehan, D. C., & Hawkins, W. G. (2007). Radical antegrade modular pancreatosplenectomy procedure for adenocarcinoma of the body and tail of the pancreas: Ability to obtain negative tangential margins. Journal of the American College of Surgeons, 204(2), 244–249.

    Article  Google Scholar 

  • Strobel, O., Buchler, M. W., & Werner, J. (2009). Duodenum-preserving pancreatic head resection: Technique according to Beger, technique according to Frey and Berne modifications. Der Chirurg, 80, 22–27.

    Article  CAS  Google Scholar 

  • Tol, J. A., Gouma, D. J., Bassi, C., Dervenis, C., Montorsi, M., Adham, M., Andrén-Sandberg, A., Asbun, H. J., Bockhorn, M., Büchler, M. W., Conlon, K. C., Fernández-Cruz, L., Fingerhut, A., Friess, H., Hartwig, W., Izbicki, J. R., Lillemoe, K. D., Milicevic, M. N., Neoptolemos, J. P., Shrikhande, S. V., Vollmer, C. M., Yeo, C. J., & Charnley, R. M. (2014). Definition of a standard lymphadenectomy in surgery for pancreatic ductal adenocarcinoma: A consensus statement by the International Study Group on Pancreatic Surgery (ISGPS). Surgery, 156(3), 591–600.

    Article  Google Scholar 

  • Warshaw, A. L. (2010). Distal pancreatectomy with preservation of the spleen. Hepatobiliary Pancreatic Surgery, 17(6), 808–812.

    Google Scholar 

  • Zhou, Y., Shi, B., Wu, L., & Si, X. (2017). A systematic review of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of the pancreas. HPB, 19(1), 10–15.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale), Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany

    Onur Bayram, Ibrahim Büdeyri, Johannes Klose & Jörg Kleeff

Authors
  1. Onur Bayram
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  2. Ibrahim Büdeyri
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  3. Johannes Klose
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  4. Jörg Kleeff
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Correspondence to Jörg Kleeff .

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Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Bayram, O., Büdeyri, I., Klose, J., Kleeff, J. (2021). Types of Pancreatic Resections. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5496-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5496-1

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