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Benign Tumors, Pathology of the Fallopian Tube

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  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

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Adenomatoid Tumor

Definition

Adenomatoid tumor is the most frequent benign neoplasm of the fallopian tube. These tumors are mesothelial in origin (Sangoi et al. 2009).

Clinical Features

  • Incidence

    These tumors are rare

  • Age

    Adenomatoid tumors usually occur in women who are in middle age or elderly. (Wachter et al. 2011.

  • Site

    Fallopian Tube

  • Clinical Presentation

    This tumor is almost always an incidental finding (Sangoi et al. 2009; Wachter et al. 2011).

  • Treatment

    Treatment is not needed (Terada 2012).

  • Outcome

    They are benign tumors (Sangoi et al. 2009; Terada 2012).

  • Macroscopy

    Tubal adenomatoid tumors are well-circumscribed, firm, masses. They typically appear as a gray, white, or yellow nodular swelling measuring 1–2 cm in diameter located beneath the tubal serosa (Karpathiou et al. 2020).

Microscopy

Tumors are characterized by anastomosing gland-like spaces that may show cribriforming and/or slit-like, ovoid to round spaces reminiscent of vascular structures. Cysts, signet-ring-like...

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References and Further Reading

  • Alvarado-Cabrero, I., Navani, S. S., Young, R. H., & Scully, R. E. (1997). Tumors of the fimbriated end of the fallopian tube: A clinicopathologic analysis of 20 cases, including nine carcinomas. International Journal of Gynecological Pathology, 16, 189–196.

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  • Bossuyt, V., Medeiros, F., Drapkin, R., et al. (2008). Adenofibroma of the fimbria: A common entity that is indistinguishable from ovarian adenofibroma. International Journal of Gynecological Pathology, 27, 390–397.

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  • Goode, B., Joseph, N. M., Stevers, M., et al. (2018). Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. Modern Pathology, 31, 660–673.

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  • Karpathiou, G., Hiroshima, K., & Peoc’h, M. (2020). Adenomatoid tumor: A review of pathology with focus on unusual presentations and sites, histogenesis, differential diagnosis, and molecular and clinical aspects with a historic overview of its description. Advances in Anatomic Pathology, 27, 394–407.

    Article  CAS  PubMed  Google Scholar 

  • Khatib, Y., Patel, R. D., Kashikar, A. S., & Chavan, K. (2015). Serous papillary cystadenofibroma of the fallopian tube: A case report and short review of the literature. Indian Journal of Pathology & Microbiology, 58, 524–527.

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  • Sangoi, A. R., McKenney, J. K., Schwartz, E. J., et al. (2009). Adenomatoid tumors of the female and male genital tracts: A clinicopathological and immunohistochemical study of 44 cases. Modern Pathology, 22, 1228–1235.

    Article  CAS  PubMed  Google Scholar 

  • Schwartz, E. J., & Longacre, T. A. (2004). Adenomatoid tumors of the female and male genital tracts express WT1. International Journal of Gynecological Pathology, 23, 123–128.

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  • Seidman, J. D., Krishnan, J., Yemelyanova, A., et al. (2016). Incidental serous tubal intraepithelial carcinoma and non-neoplastic conditions of the fallopian tubes in grossly normal adnexa: A clinicopathologic study of 388 completely embedded cases. International Journal of Gynecological Pathology, 35, 423–429.

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  • Tavares, M. A., Silva, R. C., Lourenço, M., & Ambrósio, A. (2020). Giant serous adenofibroma of the fallopian tube. BML Case Reports, 13, e234267.

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  • Terada, T. (2012). An immunohistochemical study of adenomatoid tumors of the uterus and fallopian tube. Applied Immunohistochemistry & Molecular Morphology, 20, 173–176.

    Article  CAS  Google Scholar 

  • Wachter, D. L., Wünsch, P. H., Hartmann, A., et al. (2011). Adenomatoid tumors of the female and male genital tract. A comparative clinicopathologic and immunohistochemical analysis of 47 cases emphasizing their site-specific morphologic diversity. Virchows Archiv, 458, 593–602.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Pathology, Mexican Oncology Hospital, Mexico City, Mexico

    Isabel Alvarado-Cabrero

Authors
  1. Isabel Alvarado-Cabrero
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Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Alvarado-Cabrero, I. (2022). Benign Tumors, Pathology of the Fallopian Tube. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5633-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5633-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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