Skip to main content
SpringerLink
Log in

Tumor-like Lesions, Pathology of the Broad Ligament and Other Uterine Ligaments

  • Living reference work entry
  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 4 Accesses

Adrenal Rest

Synonyms

Adrenocortical remnants

Definition

Small discrete microscopic nodules of adrenal cortical cells

Clinical Features

  • Incidence

    Adrenocortical rest have been identified in 23% of carefully sectioned broad ligaments and collections of Hilus cells are occasionally encountered (Falls 1955).

  • Site

    Broad ligament or mesosalpinx

Clinical Presentation

They are most commonly an incidental finding (Adashi et al. 1980).

  • Treatment

    None

  • Outcome

    Benign accessory tissue (Sasano et al. 1997.

Macroscopy

Grossly, they appear as small microscopic, yellow nodules, but they may be obscured by fat (Roth et al. 1996).

Microscopy

Histologically all three cortical layers are recognizable. These remnants may hypertrophy secondary to adrenal destruction or may, rarely, give rise to a functional or nonfunctional cortical adenoma (Wild et al. 1988).

Molecular Features

Not clinically relevant

Endometriosis

Definition

The presence of ectopically located endometrial tissue involving the broad...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References and Further Reading

  • Adashi, E. Y., Rosenshein, N. B., Parmley, T. H., & Woodruff, J. D. (1980). Histogenesis of the broad ligament adrenal rest. International Journal of Gynaecology and Obstetrics, 18, 102–104.

    Article  CAS  Google Scholar 

  • Falls, J. L. (1955). Accesory adrenal cortex in the broad ligament. Incidence and functional significance. Cancer, 8, 143–150.

    Article  CAS  Google Scholar 

  • Goldberg, J. M., Falcone, T., & Diamond, M. P. (2019). Current controversies in tubal disease, endometriosis, and pelvic adhesion. Fertility and Sterility, 112, 417–425.

    Article  Google Scholar 

  • Henderson, D. W., Shilkin, K. B., & Whitaker, D. (1998). Reactive mesothelial hyperplasia vs mesothelioma, including mesothelioma in situ: A brief review. American Journal of Clinical Pathology, 110(3), 397–404.

    Article  CAS  Google Scholar 

  • Kobayashi, H., Kawahara, N., Ogawa, K., & Yoshimoto, C. A. (2020). Relationship between endometriosis and obstetric complications. Reproductive Sciences, 27, 771–778.

    Article  Google Scholar 

  • Roth, L. M., Davis, M. M., & Sutton, G. P. (1996). Steroid cell tumor of the broad ligament arising in an accessory ovary. Archives of Pathology & Laboratory Medicine, 120, 405–409.

    CAS  Google Scholar 

  • Rowlands, I. J., Nagle, C. M., Spurdle, A. B., & Webb, P. M. (2011). Gynecological conditions and the risk of endometrial cancer. Gynecologic Oncology, 123, 537–541.

    Article  Google Scholar 

  • Sasano, H., Sato, S., Yajima, A., Akama, J., & Nagura, H. (1997). Adrenal rest tumor of the broad ligament: Case report with immunohistochemical study of steroidogenic enzymes. Pathology International, 47, 493–496.

    Article  CAS  Google Scholar 

  • Wild, R. A., Albert, R. D., Zaino, R. J., et al. (1988). Virilizing Para-ovarian tumors: A consequence of Nelson’s syndrome? Obstetrics and Gynecology, 71, 1053–1156.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, Mexican Oncology Hospital, Mexico City, Mexico

    Isabel Alvarado-Cabrero

Authors
  1. Isabel Alvarado-Cabrero
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Alvarado-Cabrero, I. (2022). Tumor-like Lesions, Pathology of the Broad Ligament and Other Uterine Ligaments. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5649-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5649-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation