Skip to main content
SpringerLink
Log in

Abnormal (Nonmolar) Villous Lesions, Pathology of the Placenta

  • Living reference work entry
  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 6 Accesses

Definition

Abnormal (nonmolar) villous lesion refers to a spectrum of nonmolar settings (hydropic degeneration or nonmolar fetal aneuploidy) in which a gestation exhibits chorionic villous architectural alterations that mimic partial hydatidiform mole (PHM) and/or early first trimester complete hydatidiform mole (CHM) (Fig. 1).

Fig. 1
figure 1

The chorionic villi of this non-molar gestation with fetal aneuploidy exhibit irregular contours and variable enlargement that may mimic molar pregnancy but there is no trophoblast proliferation or other classic features of molar pregnancy

Full size image

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References

  • Colgan, T. J., Chang, M. C., Nanji, S., & Kolomietz, E. (2017). DNA genotyping of suspected partial Hydatidiform moles detects clinically significant aneuploidy. International Journal of Gynecological Pathology, 36, 217–221.

    Article  CAS  PubMed  Google Scholar 

  • Vang, R., Gupta, M., Wu, L. S., Yemelyanova, A. V., Kurman, R. J., Murphy, K. M., Descipio, C., & Ronnett, B. M. (2012). Diagnostic reproducibility of hydatidiform moles: Ancillary techniques (p57 immunohistochemistry and molecular genotyping) improve morphologic diagnosis. The American Journal of Surgical Pathology, 36, 443–453.

    Article  PubMed  PubMed Central  Google Scholar 

  • WHO Classification of Tumours Editorial Board. (2020). Female genital tumours. Lyon (France): International Agency for Research on Cancer. (WHO classification of tumours series, 5th ed.; vol. 4). https://publications.iarc.fr/592.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. University of California San Francisco, San Francisco, CA, USA

    Joseph Rabban

Authors
  1. Joseph Rabban
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Joseph Rabban .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Rabban, J. (2022). Abnormal (Nonmolar) Villous Lesions, Pathology of the Placenta. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5687-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5687-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation