Definition
Allelic association refers to the statistical association between an allele and the observed phenotype. It measures the frequency of co-occurrence of the allele and observed phenotype in a population, which is more than expected and nonrandom (i.e., not by chance). It is a population-specific characteristic, hence varies among populations and doesn’t require observation of parental transmission of gametes carrying alleles.
Introduction
Allelic association is an important parameter in population genetics to investigate genetic etiology of complex traits or diseases (Lowe and Reddy 2015). An allele is each of the two or more alternative forms of a gene present at a single locus on a chromosome. Allelic association refers to the statistical association of an allele to an observed phenotype, or a trait, in a population which is more than expected and nonrandom (i.e., not by chance). In simpler terms, it is an observation that how much the variations in genotype correlate to the...
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Kulandhasamy, M., Kumar, A., Pethusamy, K., Dhiman, P. (2017). Allelic Association. In: Vonk, J., Shackelford, T. (eds) Encyclopedia of Animal Cognition and Behavior. Springer, Cham. https://doi.org/10.1007/978-3-319-47829-6_45-1
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DOI: https://doi.org/10.1007/978-3-319-47829-6_45-1
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