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Amniocentesis, also called as Amniotic Fluid Test (AFT), is an invasive prenatal medical procedure carried out primarily to diagnose chromosomal abnormalities and/or infections by using fetal DNA from the cells collected from the amniotic fluid.
Introduction
In 1956, American obstetrician Fritz Friedrich Fuchs and Danish gastroenterologist Polv Riis pioneered the technique of Amniocentesis by collecting samples to determine the fetal sex. Up until the 1970s amniotic fluid collection was done blind. In 1972, Jens Bang and Allen Northend reported that needle insertion for amniotic fluid collection could be done using ultrasound techniques.
Amniocentesis is usually reserved for those women considered at higher risk of carrying a fetus with a chromosomal or genetic abnormality. In most cases, the women are suggested to undergo amniocentesis only after genetic counseling to avoid miscarriage as a result of amniocentesis.
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References
Alfirevic, Z., Mujezinovic, F., & Sundberg, K. (2003). Amniocentesis and chorionic villus sampling for prenatal diagnosis. The Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.CD003252.
Bergman, K., Sarkar, P., O’connor, T. G., Modi, N., & Glover, V. (2007). Maternal stress during pregnancy predicts cognitive ability and fearfulness in infancy. Journal of the American Academy of Child & Adolescent Psychiatry, 46(11), 1454–1463.
Bergman, K., Sarkar, P., Glover, V., & O’Connor, T. G. (2010). Maternal prenatal cortisol and infant cognitive development: Moderation by infant–mother attachment. Biological Psychiatry, 67(11), 1026–1032.
Ogilvie, C., & Akolekar, R. (2014). Pregnancy loss following amniocentesis or CVS sampling – Time for a reassessment of risk. Journal of Clinical Medicine, 3(3), 741–746.
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Shukla, V. (2017). Amniocentesis. In: Vonk, J., Shackelford, T. (eds) Encyclopedia of Animal Cognition and Behavior. Springer, Cham. https://doi.org/10.1007/978-3-319-47829-6_57-1
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DOI: https://doi.org/10.1007/978-3-319-47829-6_57-1
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