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Calcium Phosphate Bioceramics in Biomaterials Development and Applications

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Introduction

Although bone tissue possesses the capacity for regenerative growth, the bone repair process is impaired in many clinical and pathological situations. Large bone loss caused by trauma and tumor resection and/or aging require reconstructive surgery and/or bone regeneration. At present, bone surgeons have three different possibilities when it comes to replacing bone.

Autologous bone grafts are considered as the gold standard for bone replacement, thanks to the fact that living cells are able to promote bone regeneration, in spite of large pain, septic complications, and limited amount harvested from the iliac crest or other sites. Allogenic bone graftsharvested from a cadaver or during a surgery (e.g., total hip arthroplasty) and processed by tissue banks are dead bone and have limitations because of the possible transmission of nonconventional agents or viruses, and the risk of immunological incompatibility. Xenogenic bone grafts, mainly from bovine, but also equine or...

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Abbreviations

BCP:

Biphasic calcium phosphate

CaP:

Calcium phosphate

CDA:

Calcium-deficient apatite

CHA:

Carbonated hydroxyapatite

HA:

Hydroxyapatite

IBS:

Injectable bone substitute

MBCP:

Micro-macroporous biphasic calcium phosphate

TCP:

Tricalcium phosphate

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Acknowledgements

The authors acknowledge the European Commission for financial support with program REBORNE and H2020 OrthoUnion.

Author information

Authors and Affiliations

  1. RMeS Regenerative Medicine and Skeleton, Faculté de Chirurgie Dentaire, Inserm Université de Nantes, Nantes, France

    Cyril d’Arros, Thomas Miramond & Guy Daculsi

  2. Biomatlante – Advanced Medical Solutions Group plc, ZA des 4 Nations, Vigneux de Bretagne, France

    Cyril d’Arros, Pascal Borget & Thomas Miramond

Authors
  1. Cyril d’Arros
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  2. Pascal Borget
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  3. Thomas Miramond
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  4. Guy Daculsi
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Corresponding author

Correspondence to Guy Daculsi .

Editor information

Editors and Affiliations

  1. University Leicester MRC Centre, Leicester, UK

    Gordon Roberts

  2. Dept Biochemistry, University of Oxford, Oxford, UK

    Anthony Watts

Section Editor information

  1. No affiliation provided

    Tony Cass

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d’Arros, C., Borget, P., Miramond, T., Daculsi, G. (2020). Calcium Phosphate Bioceramics in Biomaterials Development and Applications. In: Roberts, G., Watts, A. (eds) Encyclopedia of Biophysics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35943-9_698-1

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  • DOI: https://doi.org/10.1007/978-3-642-35943-9_698-1

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