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Sepsis

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Pediatric Surgery

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Abstract

Sepsis in children is a complex process that remains incompletely understood. Nevertheless, clarification in the diagnosis of sepsis and identification of host immunologic pathways as well as bacterial virulence factors have led to greatly improved understanding of the disease processes. Ultimately, this has resulted in improved management algorithms and improved outcomes with more than fivefold decrement in mortality over the last 50 years. This chapter will outline the current understanding of epidemiology, pathophysiology, management, and therapeutic strategies for pediatric sepsis.

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Authors and Affiliations

  1. Department of Pediatric Surgery, Children’s Hospital Los Angeles, 4650 Sunset Blvd. MS#75, Los Angeles, CA, 90027, USA

    Scott S. Short, Stephanie Papillon & Henri R. Ford

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  1. Scott S. Short
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  2. Stephanie Papillon
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  3. Henri R. Ford
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Correspondence to Scott S. Short .

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Editors and Affiliations

  1. Our Lady’s Children's Hospital, National Children’s Research Centre, Dublin, Ireland

    Prem Puri

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Short, S.S., Papillon, S., Ford, H.R. (2016). Sepsis. In: Puri, P. (eds) Pediatric Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38482-0_30-1

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  • DOI: https://doi.org/10.1007/978-3-642-38482-0_30-1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-38482-0

  • Online ISBN: 978-3-642-38482-0

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