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Pediatric Surgery pp 1–10Cite as

Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure

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Abstract

Recent medical advances, such as permissive hypercapnia, inhaled nitric oxide, and the use of oscillatory ventilation, have spared numerous patients from ECMO, yet many children still benefit from this modality. Patients with reversible cardiopulmonary disease, who meet criteria, should be considered ECMO candidates. As of January 2015, 27,728 neonates (74% survival) and 6,569 pediatric patients (57% survival) have been treated with ECMO for respiratory failure and 13,124 neonatal and pediatric patients for cardiac failure. ECMO provides an excellent opportunity to provide “rest” to the cardiopulmonary systems thus avoiding the additional lung or cardiac injury which otherwise would be necessary to maintain life support. This chapter outlines the indications, contraindications, management approach, and complications associated with ECMO as well as the various bypass configurations and cannulation strategies which may be employed.

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References

  • Bailly DK, Reeder RW, Zabrocki LA, Hubbard AM, Wilkes J, Bratton SL, Thiagarajan RR. Extracorporeal life support organization member centers. Development and validation of a score to predict mortality in children undergoing extracorporeal membrane oxygenation for respiratory failure: pediatric pulmonary rescue with extracorporeal membrane oxygenation prediction score. Crit Care Med. 2017;45(1):e58–66.

    Article  Google Scholar 

  • Barbaro RP, Bartlett RH, Chapman RL, et al. Development and validation of the neonatal risk estimate score for children using extracorporeal respiratory support. J Pediatr. 2016;173:56–61.e3.

    Article  Google Scholar 

  • Bartlett RH, Roloff DW, Cornell RG, et al. Extracorporeal circulation in neonatal respiratory failure: a prospective randomized study. Pediatrics. 1985;76(4):479–87.

    CAS  PubMed  Google Scholar 

  • Butler DF, Lee B, Molitor-Kirsch E, Newland JG. Extracorporeal membrane oxygenation associated bloodstream infections in children. Pediatr Infect Dis J. 2017;36:346–347.

    Article  Google Scholar 

  • Campbell BT, Braun TM, Schumacher RE, et al. Impact of ECMO on neonatal mortality in Michigan (1980–1999). J Pediatr Surg. 2003;38:290–5.

    Article  Google Scholar 

  • Extracorporeal Life Support Organization International Registry Report of the Extracorporeal Life Support Organization. 2015. University of Michigan Medical Center, Ann Arbor.

    Google Scholar 

  • Frenckner B. Extracorporeal membrane oxygenation: a breakthrough for respiratory failure. J Intern Med. 2015;278(6):586–98.

    Article  CAS  Google Scholar 

  • Hirschl RB, Bartlett RH. Extracorporeal life support in cardiopulmonary failure. In: Coran AG, Adzick NS, Krummerl T, Laberge JM, Shamberger R, Caldamone A, editors. Pediatric surgery. 5th ed. New York: Mosby; 2012. p. 89–102.

    Google Scholar 

  • Kays DW. ECMO in CDH: Is there a role? Semin Pediatr Surg. 2017;26(3):166–70.

    Article  Google Scholar 

  • Kim ES, Stolar CJ. ECMO in the newborn. Am J Perinatol. 2000;17:345–56.

    Article  CAS  Google Scholar 

  • Kim ES, Stolar CJ. Extracorporeal membrane oxygenation for neonatal respiratory failure. In: Puri P, editor. Newborn surgery. London: Arnold; 2003. p. 317–27.

    Chapter  Google Scholar 

  • Jenks CL, Rama L, Dalton HJ. Peidatric extracorporeal membrane oxygenation. Crit Care Clin. 2017;33(4):825–41.

    Article  Google Scholar 

  • McHoney M, Hammond P. Role of ECMO in congenital diaphragmatic hernia. Arch Dis Child Fetal Neonatal Ed. 2018;103(2):F178–81.

    Article  Google Scholar 

  • Madderom MJ, Reuser JJ, Utens EM, et al. Neurodevelopmental, educational and behavioral outcome at 8 years after neonatal ECMO: a nationwide multicenter study. Intensive Care Med. 2013;39(9):1584–93.

    Article  Google Scholar 

  • Schiller RM, Madderom MJ, Reuser JJ, et al. Neuropsychological follow-up after neonatal ECMO. Pediatrics. 2016;138(5):e20161313.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Colorectal Center, ECMO Program, Associate Professor of Surgery and Pediatrics, Division of Pediatric General & Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

    Jason S. Frischer

  2. Rudolph N. Schullinger emeritus Professor of Surgery and Pediatrics, Columbia University, College of Physicians and Surgeons, New York, NY, USA

    Charles J. H. Stolar

  3. California Pediatric Surgery Group, Goleta, CA, USA

    Charles J. H. Stolar

  4. Morgan Stanley Children’s Hospital, Division of Pediatric Surgery, New York, NY, USA

    Charles J. H. Stolar

  5. Section of Pediatric Surgery, C.S. Mott Children’s Hospital, University of Michigan, Ann Arbor, MI, USA

    Ronald B. Hirschl

Authors
  1. Jason S. Frischer
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  2. Charles J. H. Stolar
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  3. Ronald B. Hirschl
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Corresponding author

Correspondence to Jason S. Frischer .

Editor information

Editors and Affiliations

  1. Our Lady’s Children's Hospital, National Children’s Research Centre, Dublin, Ireland

    Prem Puri

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© 2019 Springer-Verlag GmbH Germany, part of Springer Nature

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Frischer, J.S., Stolar, C.J.H., Hirschl, R.B. (2019). Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure. In: Puri, P. (eds) Pediatric Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38482-0_58-2

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  • DOI: https://doi.org/10.1007/978-3-642-38482-0_58-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-38482-0

  • Online ISBN: 978-3-642-38482-0

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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Chapter history

  1. Latest

    Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure
    Published:
    24 December 2018

    DOI: https://doi.org/10.1007/978-3-642-38482-0_58-2

  2. Original

    Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure
    Published:
    01 March 2017

    DOI: https://doi.org/10.1007/978-3-642-38482-0_58-1

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