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Lambert-Eaton-Myastheniesyndrom

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Zusammenfassung

Das Lambert-Eaton-Syndrom (LEMS) tritt als seltene Autoimmunerkrankung gehäuft paraneoplastisch in Assoziation mit einem kleinzelligen Bronchialkarzinom auf. Klinisch besteht eine proximale belastungsabhängige Schwäche neben autonomen Störungen. Bei 85 % der Patienten sind Antikörper gegen den P/Q-Typ (synonym CaV1.2) des spannungsgesteuerten Kalziumkanals nachweisbar.

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Literatur

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Author information

Authors and Affiliations

  1. Klinik und Poliklinik für Neurologie, Martin-Luther-Universität Halle-Wittenberg, Halle, Deutschland

    Stephan Zierz

  2. Neurologische Klinik, Universitätsklinikum Heidelberg, Heidelberg, Deutschland

    Berit Jordan

Authors
  1. Berit Jordan
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  2. Stephan Zierz
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Corresponding author

Correspondence to Berit Jordan .

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Editors and Affiliations

  1. Essen, Germany

    Peter Berlit

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Jordan, B., Zierz, S. (2020). Lambert-Eaton-Myastheniesyndrom. In: Berlit, P. (eds) Klinische Neurologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44768-0_42-2

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  • DOI: https://doi.org/10.1007/978-3-662-44768-0_42-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-44768-0

  • Online ISBN: 978-3-662-44768-0

  • eBook Packages: Springer Referenz Medizin

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Chapter history

  1. Latest

    Lambert-Eaton-Myastheniesyndrom
    Published:
    08 February 2020

    DOI: https://doi.org/10.1007/978-3-662-44768-0_42-2

  2. Original

    Lambert-Eaton-Myastheniesyndrom
    Published:
    26 July 2017

    DOI: https://doi.org/10.1007/978-3-662-44768-0_42-1

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