Skip to main content
SpringerLink
Log in

Spinale Tumoren

  • Living reference work entry
  • First Online:
Klinische Neurologie

Part of the book series: Springer Reference Medizin ((SRM))

  • 898 Accesses

Zusammenfassung

Abhängig von der Lage im Spinalkanal werden intradurale und extradurale Tumoren unterschieden. Unter den extraduralen Tumoren sind Weichteiltumoren sowie primäre und sekundäre knöcherne Tumoren zu differenzieren. Intradurale Tumoren werden entsprechend ihrer Beziehung zum Rückenmark in intra- und extramedulläre Tumoren unterteilt. Es gibt zusätzliche Untergruppen: einige extramedulläre, intradurale Tumoren wachsen direkt durch die Dura hindurch oder entlang einer Nervenwurzel in den extraduralen Raum hinein. Es gibt exophytische intramedulläre Tumoren, die aus dem Rückenmark herauswachsen wie auch primäre extramedulläre Tumoren, die in das Rückenmark eindringen. Mit Ausnahme knöcherner Tumoren ist die weit überwiegende Zahl der spinalen Tumoren gutartig. Ein spinaler Tumor ist daher zuallererst eine chirurgisch zu behandelnde Erkrankung. Aussagen zur Prognose setzen eine Klärung der histologischen Diagnose voraus, die anhand der Klinik und der Bildgebung allenfalls näherungsweise getroffen werden kann.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Literatur

  • Akbar M, Eichler M, Hagmann S, Lehner B, Hemmer S, Kasperk C, Wiedenhofer B (2012) Rolle und Grenzen der Vertebro-/Kyphoplastie im Metastasenmanagement der Wirbelsäule. Orthopäde 41(8):640–646. https://doi.org/10.1007/s00132-012-1909-8

    Article  CAS  PubMed  Google Scholar 

  • Bilsky MH, Laufer I, Burch S (2009) Shifting paradigms in the treatment of metastatic spine disease. Spine (Phila Pa 1976) 34(22 Suppl):S101–S107. https://doi.org/10.1097/BRS.0b013e3181bac4b2

    Article  Google Scholar 

  • Cervoni L, Celli P, Cantore G, Fortuna A (1995) Intradural tumors of the cauda equina: a single institution review of clinical characteristics. Clin Neurol Neurosurg 97(1):8–12

    Article  CAS  Google Scholar 

  • Conti P, Pansini G, Mouchaty H, Capuano C, Conti R (2004) Spinal neurinomas: retrospective analysis and long-term outcome of 179 consecutively operated cases and review of the literature. Surg Neurol 61(1):34–43; discussion 44

    Article  Google Scholar 

  • Fischer G, Brotchi J (1996) Intramedullary spinal cord tumors. Thieme, Stuttgart

    Google Scholar 

  • Ibrahim A, Crockard A, Antonietti P, Boriani S, Bunger C, Gasbarrini A, Grejs A, Harms J, Kawahara N, Mazel C, Melcher R, Tomita K (2008) Does spinal surgery improve the quality of life for those with extradural (spinal) osseous metastases? An international multicenter prospective observational study of 223 patients. J Neurosurg Spine 8(3):271–278

    Article  Google Scholar 

  • Klekamp J (2011) Tethered cord syndrome in adults. J Neurosurg Spine 15(3):258–270

    Article  Google Scholar 

  • Klekamp J (2013) Treatment of intramedullary tumors: analysis of surgical morbidity and long-term results. J Neurosurg Spine 19(1):12–26. https://doi.org/10.3171/2013.3.spine121063

    Article  PubMed  Google Scholar 

  • Klekamp J (2015a) Spinal ependymomas. Part 2: Ependymomas of the filum terminale. Neurosurg Focus 39(2):E7. https://doi.org/10.3171/2015.5.focus15151

    Article  PubMed  Google Scholar 

  • Klekamp J (2015b) Tumoren des Spinalkanals. In: Moskopp D, Wassmann H (Hrsg) Neurochirurgie – Handbuch für die Weiterbildung und interdisziplinäres Nachschlagewerk, 2. Aufl. Schattauer Verlag, Stuttgart, S 804–825

    Google Scholar 

  • Klekamp J (2017a) A new classification for pathologies of spinal meninges-part 2: primary and secondary intradural arachnoid cysts. Neurosurgery 81:217. https://doi.org/10.1093/neuros/nyx050

    Article  PubMed  Google Scholar 

  • Klekamp J (2017b) A new classification for pathologies of spinal meninges, part 1: dural cysts, dissections, and ectasias. Neurosurgery 81:29. https://doi.org/10.1093/neuros/nyx049

    Article  PubMed  Google Scholar 

  • Klekamp J, Samii M (2007) Surgery of spinal tumors. Springer, Heidelberg

    Google Scholar 

  • Kucia EJ, Maughan PH, Kakarla UK, Bambakidis NC, Spetzler RF (2011) Surgical technique and outcomes in the treatment of spinal cord ependymomas: part II: myxopapillary ependymoma. Neurosurgery 68(1 Suppl Operative):90–94. https://doi.org/10.1227/NEU.0b013e3181fdf912; discussion 94

    Article  PubMed  Google Scholar 

  • Liljenqvist U, Schaser KD (2017) Primäre Knochentumoren. In: Börm W, Meyer F, Bullmann V, Knop C (Hrsg) Wirbelsäule interdisziplinär – Operative und konservative Therapie, 2. Aufl. Schattauer Verlag, Stuttgart, S 251–263

    Google Scholar 

  • Liljenqvist U, Lerner T, Halm H, Buerger H, Gosheger G, Winkelmann W (2008) En bloc spondylectomy in malignant tumors of the spine. Eur Spine J 17(4):600–609. https://doi.org/10.1007/s00586-008-0599-8

    Article  PubMed  PubMed Central  Google Scholar 

  • McCormick PC, Post KD, Stein BM (1990) Intradural extramedullary tumors in adults. Neurosurg Clin N Am 1(3):591–608

    CAS  PubMed  Google Scholar 

  • Meyer F, Pitzen T (2017) Sekundäre Wirbeltumoren und tumorbedingte pathologische Frakturen. In: Börm W, Meyer F, Bullmann V, Knop C (Hrsg) Wirbelsäule interdiziplinär – Operative und konservative Therapie, 2. Aufl. Schattauer Verlag, Stuttgart, S 263–270

    Google Scholar 

  • Miyazawa N, Hida K, Iwasaki Y, Koyanagi I, Abe H (2000) MRI at 1.5 T of intramedullary ependymoma and classification of pattern of contrast enhancement. Neuroradiology 42(11):828–832

    Article  CAS  Google Scholar 

  • Nakashima H, Tokunaga K, Tamiya T, Matsumoto K, Ohmoto T, Furuta T (1999) Analysis of spinal cord hemangioblastoma in von Hippel-Lindau disease. No Shinkei Geka 27(6):533–540

    CAS  PubMed  Google Scholar 

  • Pulst SM, Riccardi VM, Fain P, Korenberg JR (1991) Familial spinal neurofibromatosis: clinical and DNA linkage analysis. Neurology 41(12):1923–1927

    Article  CAS  Google Scholar 

  • Sciubba DM, De la Garza Ramos R, Goodwin CR, Xu R, Bydon A, Witham TF, Gokaslan ZL, Wolinsky JP (2016) Total en bloc spondylectomy for locally aggressive and primary malignant tumors of the lumbar spine. Eur Spine J 25(12):4080–4087. https://doi.org/10.1007/s00586-016-4641-y

    Article  PubMed  Google Scholar 

  • Souweidane MM, Benjamin V (1994) Spinal cord meningiomas. Neurosurg Clin N Am 5(2):283–291

    CAS  PubMed  Google Scholar 

  • Stein BM (1979) Surgery of intramedullary spinal cord tumors. Clin Neurosurg 26:529–542

    Article  CAS  Google Scholar 

  • Sundaresan N, Steinberger AA, Moore F, Sachdev VP, Krol G, Hough L, Kelliher K (1996) Indications and results of combined anterior-posterior approaches for spine tumor surgery. J Neurosurg 85(3):438–446

    Article  CAS  Google Scholar 

  • Tokuhashi Y, Matsuzaki H, Oda H, Oshima M, Ryu J (2005) A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine 30(19):2186–2191

    Article  Google Scholar 

  • Tomita K, Kawahara N, Kobayashi T, Yoshida A, Murakami H, Akamaru T (2001) Surgical strategy for spinal metastases. Spine (Phila Pa 1976) 26(3):298–306

    Article  CAS  Google Scholar 

  • Van Velthoven V, Reinacher PC, Klisch J, Neumann HP, Glasker S (2003) Treatment of intramedullary hemangioblastomas, with special attention to von Hippel-Lindau disease. Neurosurgery 53(6):1306–1313; discussion 1313–1304

    Article  Google Scholar 

  • Waziri A, Vonsattel JP, Kaiser MG, Anderson RC (2007) Expansile, enhancing cervical cord lesion with an associated syrinx secondary to demyelination. Case report and review of the literature. J Neurosurg Spine 6(1):52–56

    Article  Google Scholar 

  • Weller SJ, Rossitch E Jr (1995) Unilateral posterolateral decompression without stabilization for neurological palliation of symptomatic spinal metastasis in debilitated patients. J Neurosurg 82(5):739–744. https://doi.org/10.3171/jns.1995.82.5.0739

    Article  CAS  PubMed  Google Scholar 

  • Yao KC, Boriani S, Gokaslan ZL, Sundaresan N (2003) En bloc spondylectomy for spinal metastases: a review of techniques. Neurosurg Focus 15(5):E6

    Article  Google Scholar 

  • Zavala LM, Adler JR, Greene CS, Winston KR (1988) Hydrocephalus and intraspinal tumor. Neurosurgery 22(4):751–754

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Wirbelsäulenzentrum und Neurochirurgie, Christliches Krankenhaus Quakenbrück, Quakenbrück, Deutschland

    Jörg Klekamp

Authors
  1. Jörg Klekamp
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jörg Klekamp .

Editor information

Editors and Affiliations

  1. Essen, Germany

    Peter Berlit

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer-Verlag GmbH Deutschland

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Klekamp, J. (2018). Spinale Tumoren. In: Berlit, P. (eds) Klinische Neurologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44768-0_71-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-44768-0_71-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-44768-0

  • Online ISBN: 978-3-662-44768-0

  • eBook Packages: Springer Referenz Medizin

Publish with us

Policies and ethics

Search

Navigation