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Mesenchymal and Neuronal Tumors

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Braun-Falco´s Dermatology

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Abstract

Mesenchymal and neuronal neoplasms are often difficult to identify clinically. Color, location, and palpation findings of the lesion are helpful for differential diagnosis. According to the anatomical localization of mesenchymal structures, a distinction is made between neoplasms of connective tissue and fatty tissue, smooth and striated musculature, cartilage tissue and bone tissue, as well as of the peripheral nervous system. A representative tissue sample with dermatohistopathological examination is often indispensable for the precise classification of these lesions. Numerous immunohistochemical markers have proven their worth in this context. With the introduction of molecular biology, fluorescence-in-situ hybridization and reverse transcriptase-polymerase chain reactions have also become diagnostic tools for many entities. In addition, in a number of malignant neoplasms, chromosomal aberrations have prognostic and therapeutic relevance.

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Author information

Authors and Affiliations

  1. Dermatohistological Laboratory and Private Practice, Nuremberg, Germany

    Michael Wilk

  2. Clinical Department of Dermatology and Venereology, Medical University, Innsbruck, Austria

    Bernhard Zelger

Authors
  1. Michael Wilk
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  2. Bernhard Zelger
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Correspondence to Michael Wilk .

Editor information

Editors and Affiliations

  1. Department of Dermatology, University of Munich, Munich, Germany

    Gerd Plewig

  2. Department of Dermatology, University of Munich, Munich, Germany

    Lars French

  3. Department of Dermatology, University of Munich, Munich, Germany

    Thomas Ruzicka

  4. Department of Dermatology, Venerology and Allergology, Frankfurt University Hospital, Frankfurt, Germany

    Roland Kaufmann

  5. Clinic for Dermatology and Allergology, University of Marburg, Marburg, Germany

    Michael Hertl

Section Editor information

  1. Head of the Department of Dermatology, Venerology and Allergology, Frankfurt University Hospital, Frankfurt am Main, Germany

    Roland Kaufmann

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Wilk, M., Zelger, B. (2020). Mesenchymal and Neuronal Tumors. In: Plewig, G., French, L., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco´s Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-58713-3_106-1

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