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Mastocytoses

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Braun-Falco´s Dermatology

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Abstract

Mastocytosis is characterized by an increase in mast cells in one or more organs and is divided into cutaneous (mast cell accumulation in the skin) and systemic forms (mast cell accumulation in extracutaneous organs). Cutaneous forms usually develop in childhood and take a benign course, whereas the systemic disease tends to occur in adults and is usually chronic. After activation, mast cells release a multitude of different mediators; activation can take place in line with an allergic reaction, but also through physical factors, toxins, hormones or drugs. Manifestations of mastocytosis are caused by the released mediators, but can vary depending on the type of mastocytosis.

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Author information

Authors and Affiliations

  1. Dermatological Allergology, Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité – Universitätsmedizin Berlin, Berlin, Germany

    Marcus Maurer & Frank Siebenhaar

Authors
  1. Marcus Maurer
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  2. Frank Siebenhaar
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Corresponding author

Correspondence to Marcus Maurer .

Editor information

Editors and Affiliations

  1. Department of Dermatology, University of Munich, Munich, Germany

    Gerd Plewig

  2. Department of Dermatology, University of Munich, Munich, Germany

    Lars French

  3. Department of Dermatology, University of Munich, Munich, Germany

    Thomas Ruzicka

  4. Department of Dermatology, Venerology and Allergology, Frankfurt University Hospital, Frankfurt, Germany

    Roland Kaufmann

  5. Clinic for Dermatology and Allergology, University of Marburg, Marburg, Germany

    Michael Hertl

Section Editor information

  1. Head of the Department of Dermatology, Venerology and Allergology, Frankfurt University Hospital, Frankfurt am Main, Germany

    Roland Kaufmann

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Maurer, M., Siebenhaar, F. (2020). Mastocytoses. In: Plewig, G., French, L., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco´s Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-58713-3_111-1

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  • DOI: https://doi.org/10.1007/978-3-662-58713-3_111-1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-58713-3

  • Online ISBN: 978-3-662-58713-3

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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