Skip to main content

Eales’ Disease

  • Living reference work entry
  • First Online:
Book cover The Uveitis Atlas

Abstract

Eales’ disease is an idiopathic retinal vasculitis seen in young adult males and is more prevalent in the Indian subcontinent. Due to the high endemicity of tuberculosis in the Indian subcontinent, the tubercle bacilli are implicated in the pathogenesis of this condition. Due to occlusive vasculitis and retinal ischemia, this condition is characterized by development of retinal neovascularization.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Suggested Reading

  • Biswas J, Therese L, Madhavan HN. Use of polymerase chain reaction in detection of Mycobacterium tuberculosis complex DNA from vitreous sample of Eales’ disease. Br J Ophthalmol. 1999;83:994.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Biswas J, et al. Eales disease – an update. Surv Ophthalmol. 2002;47:197–214.

    Article  PubMed  Google Scholar 

  • Cai S, Su G, Li H, Xie B, Luo J. Profiling of human leukocyte antigens in Eales disease and tuberculosis. Int Ophthalmol. 2013;33:475–9.

    Article  PubMed  Google Scholar 

  • Das T, Pathengay A, Hussain N, Biswas J. Eales’ disease: diagnosis and management. Eye Lond Engl. 2010;24:472–82.

    CAS  Google Scholar 

  • El-Asrar AMA, Al-Kharashi SA. Full panretinal photocoagulation and early vitrectomy improve prognosis of retinal vasculitis associated with tuberculoprotein hypersensitivity (Eales’ disease). Br J Ophthalmol. 2002;86:1248–51.

    Article  PubMed  PubMed Central  Google Scholar 

  • Madhavan HN, Therese KL, Gunisha P, Jayanthi U, Biswas J. Polymerase chain reaction for detection of Mycobacterium tuberculosis in epiretinal membrane in Eales’ disease. Invest Ophthalmol Vis Sci. 2000;41:822–5.

    CAS  PubMed  Google Scholar 

  • Shanmugam MP, Badrinath SS, Gopal L, Sharma T. Long term visual results of vitrectomy for Eales disease complications. Int Ophthalmol. 1998;22:61–4.

    Article  CAS  PubMed  Google Scholar 

  • Shukla D, Kanungo S, Prasad NM, Kim R. Surgical outcomes for vitrectomy in Eales’ disease. Eye Lond Engl. 2008;22:900–4.

    CAS  Google Scholar 

  • Verma A, Biswas J, Dhanurekha L, Gayathri R, Lily Therese K. Detection of Mycobacterium tuberculosis with nested polymerase chain reaction analysis in enucleated eye ball in Eales’ disease. Int Ophthalmol. 2015. doi:10.1007/s10792-015-0144-9.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Parthopratim Dutta Majumder .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer (India) Pvt. Ltd.

About this entry

Cite this entry

Majumder, P.D., Biswas, J. (2017). Eales’ Disease. In: Gupta, V., Nguyen, Q., LeHoang, P., Herbort Jr., C. (eds) The Uveitis Atlas. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2506-5_83-1

Download citation

  • DOI: https://doi.org/10.1007/978-81-322-2506-5_83-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, New Delhi

  • Print ISBN: 978-81-322-2506-5

  • Online ISBN: 978-81-322-2506-5

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics